乳腺癌肿瘤血管的影像学研究及其与肿瘤分期的关系

Tumor Vessel Imaging and Its Relationship with Tumor Staging in Breast Cancers

目的 通过数字减影血管造影 (DSA)研究乳腺癌肿瘤血管影像学特征及其与肿瘤分期的关系。资料与方法 86例女性乳腺癌术前住院患者。随访术后病理 ,记录病理检查的淋巴结转移情况 ,确定腋窝淋巴结转移率和分级。影像学主要观察指标为肿瘤供血动脉的起源 ,肿瘤血管的表现。结果 动脉异常和肿瘤血管的主要表现为终末细小动脉增多 ,走行不规则 ,扭曲 ,并略增粗。有 5 4例在乳腺肿瘤发生的部位可见到不规则的血管染色团。按是否有肿瘤血管将患者分为两组 ,结果显示两组数据之间有非常显著的差别。提示肿瘤血管的出现与肿瘤大小密切相关。 86例患者中 ,病理标本发现淋巴结转移 4l例 ,其中有肿瘤血管组 33例 ,无肿瘤血管组 8例。统计结果提示肿瘤血管与淋巴结转移关系密切。结论 乳腺癌是多血供肿瘤。肿瘤血管染色的出现与肿瘤的大小有密切关系。当出现肿瘤血管时 。

Objective To observe the imaging characteristics of the tumor vessels in breast cancer with digital subtraction angiography (DSA), to study the correlation of tumor vessels with tumor staging.Materials and Methods Eight six female patients with breast cancer were enrolled in this study. After surgery, the number of examined lymph nodes and axillary metastases were recorded. The percentage of axillary lymphatic metastases and the stage of the tumor were estimated. The imaging observation was focused on the origin of the tumor feeding arteries and the morphologic features of the tumor vessels.Results The abnormal tumor vessels were mainly presented as increased, twisted and irregular small terminal arteries. Irregular mass like vascular stain was seen at tumor site in 54 cases. Significant difference in the data existed between patients showing tumor vessel stain and patients showing no tumor vessel stain, suggesting that the presence of tumor vessels had strong correlation with the size of the tumor. Of 86 patients, lymph node metastasis was seen in 41, of which 33 showed tumor vessels and 8 showed no tumor vessels. Statistic analysis indicated that a significant correlation existed between tumor vessels and lymphatic metastases. Conclusion Breast cancer has abundant blood supply. The occurrence of tumor vessel stain is well related to the tumor size. Increased lymphatic metastases may be expected in the patients who show tumor vessels on DSA.