摘要
基于光谱相关色谱方法判断复杂中药色谱指纹图谱的组分相关性 ,实现同一中药样本在不同实验条件下所得的色谱指纹图谱的相同组分的色谱保留时间漂移的局部最小二乘校正 ,为合理评价指纹图谱的品质提供较为实用的工具。
Correlation components of complicated chromatographic fingerprints of herbal medicine are determined correctly based on spectral correlative chromatography. In order to correct the shift of retention time for chromatographic fingerprints obtained under different experimental conditions, local least square method is proposed, as a practical tool, to characterize quality of fingerprints.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2004年第3期313-316,共4页
Chinese Journal of Analytical Chemistry
基金
国家自然科学基金重点资助项目 (No .2 0 175 0 3 6
No .2 0 2 3 5 0 2 0 )
关键词
中药色谱指纹图谱
组分
色谱保留时间漂移
局部最小二乘法
质量控制
色谱峰簇
相关系数
联用色谱
光谱相关色谱
Characteristic chemical fingerprints of traditional Chinese medicines,cluster of chromatographic peaks, correlation coefficient,hyphenated chromatography, local least square method, spectral correlation chromatography
