血管内超声对Radius支架近期及远期效果的研究

Observation of recent and long-term effects of Radius stent by intravascular ultrasound

目的 探讨血管内超声评价Radius支架的近期及远期效果的价值。方法 14 7例冠心病患者 186处病变择期置入自扩张Radius支架 ,在支架置入前、置入后即刻及置入后 6个月进行冠状动脉造影及血管内超声检查 ,同时进行临床随访 ,观察Radius支架的近期及远期效果。结果 对 14 7例患者 186处病变 ,Radius支架的置入成功率为 99.5 % ,临床成功率为 98.9% ,6.4个月后复查再狭窄率为 10 .8% ;血管内超声显示 ,治疗前血管内腔面积平均为 2 .7mm2 ,在支架留置后即刻面积扩大为 5 .3mm2 ,约 6.4个月后复查支架面积扩大至7.6mm2 ,但因支架内新增生的内膜面积为 2 .6mm2 ,最终血管内腔面积为 5 .0mm2 ,比支架留置后即刻略小。结论 Radius支架再狭窄发生率低 ,血管内超声对观察Radius支架再狭窄发生有一定的应用价值。

Objective To investigate the recent and long term effects of Radius stent through intravascular ultrasound(IVUS).Methods The study consisted of 147 coronary disease patients who had implanted self expanding Radius stent in chosen time.Coronary artery angiography and IVUS were performed to evaluate the clinical outcomes of Radius stent before and after the implantation.All the patients were followed up six months approximately after the implantation.Results The implantation success rate and clinical success rate of Radius stent were 99.5% and 98.9% respectively, restenosis rate was 10.8% at follow up examination for 6.4 months.The IVUS measurements showed that the lumen area was extended from 2.7 mm 2 to 5.3 mm 2 after the implantation and stent area was 7.6 mm 2 after about 6.4 months,but since intimal hyperplasia area was 2.6 mm 2,real lumen area was 5.0 mm 2 at follow up, which was a little smaller than that of the stent implantation at once.Conclusions IVUS showed a lower occurrence of restenosis for Radius stent,which is of value to its clinical application.