脂肪肝与高血压关系的人群研究

INVESTIGATION OF THE RELATION BETWEEN FATTY LIVER AND HYPERTENSION IN BEIJING, CHINA

通过1051人的流行病学调查发现,脂肪肝组的高血压患病率(26.7％)明显高于非脂肪肝组(9.7％)。在Logistic回归校正多个危险因素后,脂肪肝对高血压病的Odds Ratio为2.326,P<0.001。用前进法证实脂肪肝是一个独立的高血压病的危险因素。用两种方法证实年龄、体重指数对高血压病的危险性约为脂肪肝的4～5倍,父母高血压史、高脂血症和性别分别为脂肪肝的4/5、3/5和2/5。

The relation between fatty liver and hypertension was studied in a group of 1051 health examina-tion participants in Beijing, China. A cross-sectional design was used in which blood pressure weredetermined and questionnaires administered to the participants over a two month period. The prevalenceof hypertension was found in 26.7K in the fatty liver participants and 9.7% in the non-fatty liverparticipants with a fatty liver/non-fatty liver ratio of about 2.75, P<0 .01. Logistic regression indi-cated that the odds ratio of fatty liver was 2.326(P<0.001), which was adjusted by age, sex and par-ents hypertensive history. It suggested that the fatty liver was an independent risk factor for hypertensionLogistic regression also indicated that the contribution of age and body mass index on the probabilityof hypertension was about 4～5 times than fatty liver, the contribution of parents hypertensive history.hyperlipaemia and sex was about 4/5, 3/5 and 2/5 times than fatty liver.