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Squamous Cell Carcinoma of the Middle Ear: Case Report and Literature Review

Squamous Cell Carcinoma of the Middle Ear: Case Report and Literature Review
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摘要 Malignant tumors originating from the middle ear are rare. The literature identifies chronic inflammation and Human Papillomavirus (HPV) infection as the most common risk factors. A CT scan to assess bony invasion and an MRI to evaluate soft tissue involvement, depth of invasion, and perineural invasion, followed by a biopsy, are indispensable for diagnosis and treatment. There is no standard treatment for squamous cell carcinoma of the middle ear, however, most reported cases are treated with surgical resection followed by postoperative radiotherapy. Given the challenges of achieving complete surgical excision, radiotherapy plays a crucial role in controlling middle ear cancers, as demonstrated in our case. We present a case of squamous cell carcinoma of the middle ear in a 63-year-old female with a history of chronic suppurative otitis media. The patient underwent a right subtotal petrosectomy without lymph node dissection followed by concurrent chemoradiotherapy. At the one-year follow visit, no recurrence or metastasis was detected. Malignant tumors originating from the middle ear are rare. The literature identifies chronic inflammation and Human Papillomavirus (HPV) infection as the most common risk factors. A CT scan to assess bony invasion and an MRI to evaluate soft tissue involvement, depth of invasion, and perineural invasion, followed by a biopsy, are indispensable for diagnosis and treatment. There is no standard treatment for squamous cell carcinoma of the middle ear, however, most reported cases are treated with surgical resection followed by postoperative radiotherapy. Given the challenges of achieving complete surgical excision, radiotherapy plays a crucial role in controlling middle ear cancers, as demonstrated in our case. We present a case of squamous cell carcinoma of the middle ear in a 63-year-old female with a history of chronic suppurative otitis media. The patient underwent a right subtotal petrosectomy without lymph node dissection followed by concurrent chemoradiotherapy. At the one-year follow visit, no recurrence or metastasis was detected.
作者 Mariam Harrak Khouloud Ziani Madiha Chelakhi Othmane Saqri Nabila Sellal Mohamed El Hfid Mariam Harrak;Khouloud Ziani;Madiha Chelakhi;Othmane Saqri;Nabila Sellal;Mohamed El Hfid(Department of Radiotherapy, University Hospital Mohamed VI of Tangier, Tangier, Morocco)
出处 《Journal of Cancer Therapy》 2024年第9期303-310,共8页 癌症治疗(英文)
关键词 Chronic Suppurative Otitis The Middle Ear Squamous Cell Carcinoma SURGERY RADIOTHERAPY Chronic Suppurative Otitis The Middle Ear Squamous Cell Carcinoma Surgery Radiotherapy
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