摘要
Adult Nephrotic Syndrome (NS) is defined by proteinuria > 3 g/24h or 50 mg/kg/day, hypoprotidemia < 60 g/24h, hypoalbuminemia < 30 g/L. It is a disease with high thromboembolic risk. Peripheral vein thrombosis is common, while its association with pulmonary localizations has been more rarely reported. We report a case of nephrotic syndrome revealed by an association of pulmonary embolism, renal vein and inferior vena cava thrombosis. The diagnosis was confirmed by thoracic angioscan. Renal biopsy revealed Focal Segmental Hyalinosis (FSH). An anti-coagulant treatment and an anti-proteinuric treatment were instituted based on a calcium channel blocker (amlodipine) associated with the conversion enzyme inhibitor (perindopril).
Adult Nephrotic Syndrome (NS) is defined by proteinuria > 3 g/24h or 50 mg/kg/day, hypoprotidemia < 60 g/24h, hypoalbuminemia < 30 g/L. It is a disease with high thromboembolic risk. Peripheral vein thrombosis is common, while its association with pulmonary localizations has been more rarely reported. We report a case of nephrotic syndrome revealed by an association of pulmonary embolism, renal vein and inferior vena cava thrombosis. The diagnosis was confirmed by thoracic angioscan. Renal biopsy revealed Focal Segmental Hyalinosis (FSH). An anti-coagulant treatment and an anti-proteinuric treatment were instituted based on a calcium channel blocker (amlodipine) associated with the conversion enzyme inhibitor (perindopril).
作者
Sah Dit Baba Coulibaly
Magara Samaké
Aboubacar Sidiki Fofana
Seydou Sy
Hamadoun Yattara
Nanko Doumbia
Katilé Drissa
Moctar Coulibaly
Kodio Atabieme
Djénéba Maiga
Aboudou Messoum Dolo
Nouhoum Coulibaly
Hamat Ibrahim
Saharé Fongoro
Konaté Anselme
Sah Dit Baba Coulibaly;Magara Samaké;Aboubacar Sidiki Fofana;Seydou Sy;Hamadoun Yattara;Nanko Doumbia;Katilé Drissa;Moctar Coulibaly;Kodio Atabieme;Djénéba Maiga;Aboudou Messoum Dolo;Nouhoum Coulibaly;Hamat Ibrahim;Saharé Fongoro;Konaté Anselme(Nephrology Unit of Somino DOLO Hospital, Mopti, Mali;Nephrology Unit of the Fousseyni DAOU Hospital, Kayes, Mali;National Center for Scientific and Technological Research (CNRST), Bamako, Mali;Faculty of Medicine of Bamako, Bamako, Mali;Department of Nephrology and Haemodialysis, University Teaching Hospital of Point-G, Bamako, Mali;Medicine Department of Mali Hospital, Bamako, Mali;Gastrohepato-Enterology Unit of the Fousseyni DAOU Hospital, Kayes, Mali;Nephrology Unit of the Mali GAVARDO Hospital of Sebenicoro, Bamako, Mali;Nephrology Unit of Sikasso Hospital, Sikasso, Mali;Department of Nephrology-Hemodialysis, National General Reference Hospital, N'Djamena, Chad;Department of Gastro-Hepato-Enterology, Gabriel Touré University Hospital, Bamako, Mali)
