摘要
In the last two decades the study of red blood cell elasticity using optical tweezers has known a rise appearing in the scientific research with regard to the various works carried out. Despite the various work done, no study has been done so far to study the influence of friction on the red blood cell indentation response using optical tweezers. In this study, we have developed a new approach to determine the coefficient of friction as well as the frictional forces of the red blood cell. This approach therefore allowed us to simultaneously carry out the indentation and traction test, which allowed us to extract the interfacial properties of the microbead red blood cell couple, among other things, the friction coefficient. This property would be extremely important to investigate the survival and mechanical features of cells, which will be of great physiological and pathological significance. But taking into account the hypothesis of friction as defined by the isotropic Coulomb law. The experiment performed for this purpose is the Brinell Hardness Test (DB).
In the last two decades the study of red blood cell elasticity using optical tweezers has known a rise appearing in the scientific research with regard to the various works carried out. Despite the various work done, no study has been done so far to study the influence of friction on the red blood cell indentation response using optical tweezers. In this study, we have developed a new approach to determine the coefficient of friction as well as the frictional forces of the red blood cell. This approach therefore allowed us to simultaneously carry out the indentation and traction test, which allowed us to extract the interfacial properties of the microbead red blood cell couple, among other things, the friction coefficient. This property would be extremely important to investigate the survival and mechanical features of cells, which will be of great physiological and pathological significance. But taking into account the hypothesis of friction as defined by the isotropic Coulomb law. The experiment performed for this purpose is the Brinell Hardness Test (DB).
作者
Edoukoua Jean Michel Konin
Pavel Yale
Abadê Ange-Boris N’guessan
Kouassi Benoit Kouakou
Abaka Michel Kouacou
Eugene Megnassan
Edoukoua Jean Michel Konin;Pavel Yale;Abadê Ange-Boris N’guessan;Kouassi Benoit Kouakou;Abaka Michel Kouacou;Eugene Megnassan(Département des Sciences et Techniques, Université Alassane Ouattara, Bouaké, Cô,te d’Ivoire;Laboratoire d’Instrumentation, Image et Spectroscopie (L2IS), Institut National Polytechnique, Félix Houphouë,t-Boigny (INPHB), Yamoussoukro, Cô,te d’Ivoire;Classes préparatoires aux grandes Ecoles, Université de San Pedro, San Pedro, Cô,te d’Ivoire;Laboratoire de Physique Fondamentale et Appliquée, Université Nangui Abrogoua (UNA), Abidjan, Cô,te d’Ivoire)
