摘要
国内外应用激光激发荧光于肿瘤的研究已有一定进展,但多采用血卟啉等光敏物质来鉴别肿瘤组织。对于肿瘤固有荧光的研究还刚开端,初步表明激光激发癌肿组织所观察到的特殊性荧光和光谱,可用于癌肿的早期诊断,对于各种病理因素与胃癌荧光光谱峰值变化的较系统研究报道较少。本文用新鲜胃癌手术标本为材料,检测固有荧光对胃癌诊断的价值,并着重分析一些病理学因素与荧光强度的关系。
Nlaser activated autofluorescence of freshly resected 16 gastric cancer and 2 benigngastric ulcer specimens were studied both by naked-eye observation and spectroscopy,emphasing on the relationship beween pathological effect and peak-value spectra recordedin the cancerous regions.Positive results as shown by orange-red fluorescence with nakedeye had been recorded with an accordance rate of 83.3%.Meanwhile,in spectral study,atotal of 115 detecting points of these 18 cases with a total accordance rate of 89.6%hadshown the presence of a characteristic peak at 5900A in gastric cauncerous regions or theabsence in normal non-cancerous tissues either at the surrounding or the non-cancerousregion suggesting that this method has a,definite value in the diagnosis of gastric cancer.The study of 76 detecting points from 16 proven gastric cancers revealed that certainrelations existed between fluorescent intensity of the cancerous peak and the followingpathological features,namely:histological types;number of cancerous cells;thickness ofthe covering mucous membrane and"activities"of the cancerous cells.
出处
《肿瘤》
CAS
1987年第3期108-110,144,共4页
Tumor
