棕榈油酸功能的研究进展

Progress in the function of palmitoleic acid

omega-7脂肪酸是一组单不饱和脂肪酸,常见于深海鱼类(如凤尾鱼)和某些植物类食品(澳洲坚果油、沙棘果油、海藻等)中。近年来,omega-3、omega-6和omega-9脂肪酸的作用都为人所熟识,但omega-7脂肪酸的众多功效却少有人知道。omega-7脂肪酸不仅可以控制体重,改善皮肤状况,提高人体对胰岛素的敏感性,降低肝脂肪的蓄积和减少炎症,并且可以降低低密度脂蛋白胆固醇,增加高密度脂蛋白胆固醇,改善冠状动脉心脏疾病和高血压等。我国人口快速老龄化,患糖尿病、高脂血症等代谢综合征数量急剧增加,对以棕榈油酸为主的omega-7脂肪酸保健产品以及医药制剂有更大的需求。对棕榈油酸在控制体重、改善皮肤状况、预防动脉粥样硬化、改善代谢综合征与炎症、防止骨碎、改善干眼症等方面的功能研究现状及可能存在的消极作用进行综述,旨在为omega-7脂肪酸功能性产品开发提供参考。

omega-7 fatty acids are a group of monounsaturated fatty acids,commonly found in deep-sea fish(such as anchovies)and in certain plant foods(macadamia oil,seabuckthorn fruit oil,seaweed,etc.).In recent years,the roles of omega-3,omega-6 and omega-9 fatty acids have been well known,but the effects of omega-7 fatty acids are rarely known.omega-7 fatty acids not only can control weight,improve skin conditions,increase insulin sensitivity in human body and help to reduce the accumulation of liver fat and inflammation,but also can reduce low density lipoprotein,increase high density lipoprotein and improve coronary heart disease and hypertension.The population of China is aging rapidly,and the number of people suffering from diabetes of mellitus,hyperlipidemia and other metabolic syndrome grow rapidly,so there is a greater demand for omega-7 fatty acids health products and pharmaceutical preparations.The current research status of palmitoleic acid on weight control,skin conditions improvement,atherosclerosis prevention,improvement of metabolic syndrome and inflammation,bone fragmentation prevention,and dry eye syndrome improvement and its possible negative effects function were reviewed in order to provide references for the development of omega-7 fatty acids functional products.