脑蛋白水解物联合康复训练治疗小儿脑瘫患儿的临床效果

Clinical Effects of Cerebroprotein Hydrolysate Combined with Rehabilitation Training on Children with Cerebral Palsy

目的探讨脑蛋白水解物联合康复训练治疗小儿脑瘫患儿的临床疗效。方法选取2017年3月至2019年3月解放军总医院第七医学中心附属八一脑科医院收治的小儿脑瘫患儿88例作为研究对象,按随机数字表法分为两组,对照组44例患儿采用常规康复训练治疗,试验组患儿在对照组康复训练基础上予以脑蛋白水解物治疗,比较两组临床疗效、精细运动功能(FMFM)评分、粗大运动功能评估表(GMFM-88)评分及DQ指数。结果试验组患儿治疗有效率(95.45%)显著高于对照组(68.18%),差异有统计学意义(P<0.05);治疗6个疗程后,试验组患儿的FMFM评分、GMFM-88评分及DQ指数显著高于对照组,差异有统计学意义(P<0.05)。结论脑蛋白水解物联合康复训练治疗可有效提高小儿脑瘫患儿的运动功能,效果显著。

Objective To explore the clinical effects of cerebroprotein hydrolysate combined with rehabilitation training on children with cerebral palsy.Methods A total of 88 children with cerebral palsy admitted to Bayi Brain Hospital Affiliated to the Seventh Medical Center of PLA General Hospital from March 2017 to March 2019 were selected as the research objects.According to the method of random number table,they were divided into 2 groups.A total of 44 children in the control group were treated with routine rehabilitation training.The children in the test group were treated with cerebroprotein hydrolysate on the basis of rehabilitation training in the control group.The clinical efficacy,fine motor function(FMFM)score,GMFM-88 score,and DQ index were compared between the 2 groups.Results the total effective rate(95.45%)of clinical treatment in the experimental group was significantly higher than that in the control group(68.18%),and the difference was statistically significant(P<0.05).And after 6 courses of treatment,the FMFM score,GMFM-88 score and DQ index of the children in the test group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Brain protein hydrolysate combined with rehabilitation training can effectively improve the motor function of children with cerebral palsy,with significant effect.