临床药师对1例溃疡性结肠炎合并慢性乙肝患者的SOAP模式药学监护

Pharmaceutical Care of Clinical Pharmacist with the SOAP Model for a Patient with Ulcerative Colitis Complicated with Chronic Hepatitis B

炎症性肠病是一种慢性非特异性肠道炎症性疾病,包括溃疡性结肠炎和克罗恩病。肝炎病毒感染是炎症性肠病患者中常见的病毒感染之一。炎症性肠病合并乙肝病毒感染的患者由于接受免疫抑制药或生物制剂治疗可能会导致乙肝病毒复制活跃、肝功异常,甚至肝衰竭的风险。临床药师结合溃疡性结肠炎及慢性乙肝的治疗原则和诊疗方案,运用SOAP工作模式参与1例溃疡性结肠炎合并慢性乙肝患者的治疗药物调整,并对药物疗效及不良反应等实施全程药学监护,及时发现药物治疗问题,向医师提出合理建议保证患者用药安全性和有效性。

Hepatitis virus infection is one of the common viral infections in patients with inflammatory bowel disease(IBD).Because of the treatment with immunosuppressants or biological agents,patients with IBD and hepatitis B virus infection may have the risk of active hepatitis B virus replication,abnormal liver function,and even liver failure.Referring to the diagnosis and treatment principles of ulcerative colitis and chronic hepatitis B,clinical pharmacists participated in the adjustment of drugs for such a patient and implemented full-scale pharmaceutical monitoring for drug efficacy and adverse drug reactions.By promptly discovering the patient’s drug treatment problems by using the SOAP model,clinical pharmacist made reasonable recommendations to physicians,thus ensuring the safety and effectiveness of the patient’s medication.