“形神共调”针法联合当归饮子治疗慢性荨麻疹血虚风燥证的临床观察

Clinical Observation on Treatment of Chronic Urticaria of Blood Deficiency Wind Dryness Syndrome with Acupuncture Method of“Regulating Body and Mind”Combined with Danggui Yinzi(当归饮子)

目的观察“形神共调”针法联合当归饮子治疗慢性荨麻疹血虚风燥证的临床疗效及其机理。方法血虚风燥型慢性荨麻疹患者58例,随机分成观察组30例、对照组28例,对照组给予常规针刺法联合当归饮子内服,观察组给予“形神共调”针法联合当归饮子内服,两组均连续治疗6周。采用荨麻疹活动性评分(UAS)、汉密尔顿焦虑量表(HAMA)、皮肤病生活质量量表(DQLS)评价两组干预办法对慢性荨麻疹的疗效,检测患者血清补体C3、C4以及C反应蛋白(CRP)的水平。结果与治疗前比较,治疗6周后两组患者UAS、HAMA以及DQLS评分均明显降低(P<0.05);与对照组比较,治疗6周后观察组患者UAS、HAMA、DQLS评分以及血清CRP均明显降低(P<0.05),而血清C3、C4水平明显升高(P<0.05)。结论“形神共调”针法联合当归饮子可明显改善血虚风燥型慢性荨麻疹患者的疾病活动度,减轻患者瘙痒引起的焦虑状态,从而提高患者生活质量,且该作用机制与降低血清CRP含量、提高血清C3与C4水平有关。

Objective To observe the clinical efficacy and mechanism of"regulating body and mind"acupuncture combined with Danggui Yinzi(当归饮子)in the treatment of chronic urticaria of blood deficiency wind dryness syndrome.Methods Fifty-eight patients with chronic urticaria of blood deficiency and wind dryness syndrome were randomly divided into the observation group(30 cases)and the control group(28 cases).The control group was treated with conventional acupuncture combined with Danggui Yinzi orally,and the observation group was treated with"regulating body and mind"acupuncture combined with Danggui Yinzi orally.Both groups were treated for 6 weeks.Urticaria activity score(UAS),Hamilton Anxiety Scale(HAMA)and dermatology quality of life scale(DQLS)were used to evaluate the efficacy of the two groups on chronic urticaria,and the levels of serum complement C3,C4 and C-reactive protein(CRP)were detected.Results Compared with those before treatment,the scores of UAS,HAMA and DQLS of the two groups were significantly decreased after 6 weeks of treatment(P<0.05).Compared with those of the control group,the scores of UAS,HAMA,DQLS and the serum level of CRP in the observation group were significantly decreased after 6 weeks of treatment(P<0.05),while the serum levels of C3 and C4 were significantly increased(P<0.05).Conclusion The"regulating body and mind"acupuncture combined with Danggui Yinzi can significantly reduce the disease activity and the anxiety state caused by pruritus of patients with chronic urticaria of blood deficiency and wind dryness syndrome and improve the quality of life of patients,and the mechanism is related to reducing the content of serum CRP and increasing the levels of serum C3 and C4.