河北省成年居民物质所致精神障碍的影响因素分析

Influencing factors for substance-induced psychotic disorders among adults in Hebei Province

目的了解河北省成年居民物质所致精神障碍情况,并分析其影响因素,为制订物质所致精神障碍防制策略提供依据。方法采用多阶段分层随机抽样方法,在河北省城市和农村逐层选取≥18岁常住居民为调查对象,采用自行设计的一般情况问卷收集人口学资料,采用一般健康问卷12项(GHQ-12)和8个有关精神障碍危险因素问卷收集物质所致精神障碍情况;采用多因素Logistic回归模型分析物质所致精神障碍的影响因素。结果发放问卷23675份,回收有效问卷20884份,回收有效率为88.21%。居民物质所致精神障碍终生患病率加权后为6.20%,其中酒精、镇静剂/催眠药/抗焦虑药和其他物质所致精神障碍的终生患病率加权后分别为5.93%、0.24%和0.04%。多因素Logistic回归分析结果显示,年龄(35~<45岁,OR=1.582,95%CI:1.091~2.292;45~<60岁,OR=2.185,95%CI:1.524~3.132;≥60岁,OR=2.061,95%CI:1.422~2.986)、男性(OR=10.832,95%CI:8.265~14.196)、居住在城市(OR=1.431,95%CI:1.202~1.703)、非贫困家庭(OR=2.291,95%CI:1.652~3.177)、有躯体疾病(OR=2.028,95%CI:1.678~2.452)和有遗传病史(OR=1.574,95%CI:1.181~2.098)与物质所致精神障碍存在统计学关联。结论河北省成年居民物质所致精神障碍终生患病率为6.20%,患病风险与年龄、性别、地区、家庭经济状况、躯体疾病史和遗传病史相关。

ObjectiveTo investigate the status and influencing factors of substance-induced psychotic disorders in residents over 18 years old in Hebei Province,and to provide evidence for the prevention and control of substance-induced psychotic disorders.Methods Using multi-stage stratified random sampling method,the permanent residents aged 18 years and over were selected from urban and rural areas in Hebei Province.The demographic data was collected,the 12-Item General Health Questionnaire(GHQ-12)and eight risk factors about mental disorder questionnaire were used to find out mental disorders.The multivariate logistic regression model was conducted to analyze the influencing factor for substance-induced psychotic disorders.Results A total of 23675 questionnaires were sent out,20884 were valid(88.20%).The weighted lifetime prevalence rates of substance-induced psychotic disorders,alcohol-related disorders,sedatives/hypnotics/anti-anxiety disorders and other substance-induced psychotic disorders were 6.20%,5.93%,0.24%and 0.04%,respectively.Multivariate logistic regression analysis showed that age(35-<45,OR=1.582,95%CI:1.091-2.292;45-<60,OR=2.185,95%CI:1.524-3.132;≥60,OR=2.061,95%CI:1.422-2.986),males(OR=10.832,95%CI:8.265-14.196),urban area(OR=1.431,95%CI:1.202-1.703),non-poor family(OR=2.291,95%CI:1.652-3.177),physical diseases(OR=2.028,95%CI:1.678-2.452)and genetic history(OR=1.574,95%CI:1.181-2.098)were the influencing factors for substance-induced psychotic disorders.Conclusion The lifetime prevalence of substance-induced psychotic disorders among residents aged 18 years and over in Hebei Province is 6.20%,which is mainly related to age,gender,region,family economic situation,physical disease history and genetic history.