木豆枝叶的化学成分研究

Chemical Constituents from the Twigs and Leaves of Cajanus cajan

目的:研究木豆Cajanus cajan(L.)Millsp.的化学成分。方法:采用结晶、重结晶、硅胶柱层析、Sephadex LH-20葡聚糖凝胶柱层析、MCI柱层析及HPLC对木豆茎叶进行分离纯化,并运用波谱学方法对所得到的化合物进行结构鉴定。结果:从木豆枝叶中分离得到13个化合物,经波谱解析分别鉴定为:Iseluxine(1)、Trolline(2)、烟酰胺(3)、淫羊藿苷A;(4)、(+)-松脂素(5)、(+)-异落叶松树脂醇(6)、4-Ketopinoresionl(7)、五味子苷(8)、4-甲氧基邻苯二酚(9)、3,4-二羟基苯甲醛(10)、Alternariol(11)、α-Tocopherol(12)、Tocopherylquinone(13)。结论:化合物1~13均为首次从该植物中分离得到。

Objective:To study the chemical constituents from the twigs and leaves of Cajanus cajan.Methods:Crystallization,recrystallizition,column chromatography filled with silica gel,Sephadex LH-20,MCI and HPLC were used for isolation and purification.The structures of the compounds were identified by spectroscopic method.Results:Thirteen compounds were isolated from the twigs and leaves of Cajanus cajan and identified as iseluxine(1),trolline(2),nicotinamide(3),icariol A;(4),(+)-lyoniresinol(5),(+)-isolariciresinol(6),4-ketopinoresionl(7),(+)-isolariciresinol-2α-O-β-D-xylopyranside(8),4-methoxycatechol(9),3,4-dihydroxybenzene formaldehyde(10),alternariol(11),α-tocopherol(12),tocopherylquinone(13),respectively.Conclusion:Among them,compounds 1 to 13 are isolated from Cajanus cajan for the first time.