Cardiovascular magnetic resonance imaging characteristics and influence factors of aortic insufficiency patients with myocardial fibrosis

Objective To investigate the cardiovascular magnetic resonance(CMR)imaging characteristics and influence factors of aortic insufficiency(AI)patients with myocardial fibrosis.Methods This retrospective study included 59 AI patients who received CMR and transthoracic echocardiography(TTE)examinations from June 2011 to February 2015.AI patients were divided into 2 groups:bicuspid aortic valve(BAV)group(n=30)and non-BAV group(n=29).Patients were also divided into late gadolinium enhancement(LGE)group(n=27)and non-LGE group(n=32).The baseline clinical characteristics were collected through electronic medical records.Hemodynamic parameters such as grade of AI,cardiac functional parameters and LGE mass fraction(LGE%)were measured by CMR post-processing analysis.Kappa test was used to assess the consistency of AI severity between CMR and TTE.