The role of mesenchymal stem cells in allogeneic hematopoietic stem cell transplantation for patients with refractory severe aplastic anemia

Objective To evaluate the efficacy and safety ofmesenchymal stem cells in allogeneic hematopoietic stemcell transplantation for patients with refractory severeaplastic anemia(R-SAA).MethodsThe clinical data of25 R-SAA patients receiving co-transplantation of mesen-chymal stem cells combined with peripheral blood stem cells from sibling donors(10 cases)and unrelated donors(15 cases)from March 2010 to July 2018 in Zhengzhou University Affiliated Tumor Hospital were retrospectively analyzed.