中医定向透药联合手指操对类风湿性关节炎女性患者手关节功能康复效果的影响

Effect of directional drug therapy of traditional Chinese medicine combined with finger exercises on functional rehabilitation of hand joints in female patients with rheumatoid arthritis

目的分析中医定向透药联合手指操对类风湿性关节炎(RA)女性患者手关节功能康复效果的影响。方法选取天津市第一中心医院于2020年1~12月收治的80例RA女性患者,采用随机数字表法分为对照组(40例)和观察组(40例)。2组患者均采用手指操进行干预,观察组患者加用中医定向透药进行干预。比较2组患者的临床疗效、关节恢复状况、手功能障碍(SOFI)评分、视觉模拟评分法(VAS)评分及关节症状改善状况。结果观察组的临床总有效率为92.50%,较对照组的75.00%高(P<0.05)。干预10 d后,2组的晨僵时间均较同组干预前缩短(P均<0.05),握力值均较同组干预前增加(P均<0.05),手功能SOFI和VAS评分均较同组干预前降低(P均<0.05),关节肿胀个数、关节疼痛个数均较同组干预前减少(P均<0.05);观察组的晨僵时间较对照组短(P<0.05),握力值较对照组大(P<0.05),手功能SOFI和VAS评分均较对照组低(P均<0.05),关节肿胀个数、关节疼痛个数均较对照组少(P均<0.05)。结论中医定向透药联合手指操应用于RA女性患者中,可提高临床疗效,缩短晨僵时间,增加握力值,改善手功能、关节肿胀及疼痛情况。

Objective To analyze the effect of directional drug therapy of traditional Chinese medicine combined with finger exercises on the functional rehabilitation of hand joints in female patients with rheumatoid arthritis(RA).Method Eighty female patients with RA who were admitted to Tianjin First Central Hospital from January to December 2020 were included in the study and allocated into a control group(40 cases)and an observation group(40 cases)by random number table method.Both groups were intervened by finger exercises,and the observation group was additionally intervened by directional drug therapy of traditional Chinese medicine.The clinical efficacy,joint recovery,signals of functional impairment(SOFI)score,visual analogue scale(VAS)score,and improvement of joint symptoms were compared between the two groups.Results The overall clinical effective rate of the observation group was 92.50%,which was higher than 75.00%of the control group(P<0.05).After10 days of intervention,the duration of morning stiffness in both groups was shortened compared with that before intervention(both P<0.05).The hand grip strength value was increased compared with that before intervention(both P<0.05).The SOFI and VAS scores were decreased compared with those before intervention(all P<0.05).The swollen joint counts and tender joint counts were decreased compared with those before intervention(all P<0.05).The duration of morning stiffness of the observation group was shorter than that of the control group(P<0.05).The hand grip strength value was higher than that of the control group(P<0.05).The SOFI and VAS scores were lower than those of the control group(both P<0.05).The swollen joint counts and tender joint counts were less than those of the control group(both P<0.05).Conclusion The application of directional drug therapy of traditional Chinese medicine combined with finger exercises in female patients with RA can improve the clinical efficacy,shorten the duration of morning stiffness,increase the hand grip strength,and improve the hand function,joint swelling and tenderness.