沙门菌血清型■,4,[5],12∶i∶-的流行病学特征研究进展

The epidemic characteristics of Salmonella serotype ■,4,[5],12 ∶ i ∶-

在过去的二十多年,沙门菌血清型■,4,[5],12∶i∶-不断被全球多个国家或地区检出,现已成为引起人类感染性腹泻的主要血清型之一。沙门菌血清型■,4,[5],12∶i∶-与鼠伤寒沙门菌比较,除了缺少第Ⅱ相鞭毛抗原表达,其病原学及遗传学特征与鼠伤寒沙门菌十分相似,一直被认为由鼠伤寒沙门菌发生多个独立遗传变异事件进化而来,属于多个克隆或克隆系。本文就沙门菌血清型■,4,[5],12∶i∶-在人群感染、食品及动物源方面的流行病学特征进行综述,为该血清型的感染防控工作以及科学研究提供数据支持。

Over the last two decades,Salmonella■,4,[5],12∶i∶-has been frequently detected in many countries or regions around the world,and nowadays it has become one of the major serotypes responsible for human infectious diarrhea.The etiology and genetic features of Salmonella■,4,[5],12∶i∶-is quite similar with Salmonella Typhimurium(■,4,[5],12∶i∶1,2)but lacking the second phase flagellar antigen.It has evolved from Salmonella Typhimurium through multiple independent events involving different clonal groups or multiple clones.In this study,we reviews the epidemic characteristics including human infections,animal and animal-derived foods of Salmonella■,4,[5],12∶i∶-,providing support for the prevention and control of infection and scientific researches.