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蒙药阿拉坦五味丸对LPS诱导RAW264.7细胞的抗炎作用

Anti-inflammatory effect of Mongolian medicine Alatan Wuwei pill on LPS-induced RAW264.7 cells
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摘要 目的:探究蒙药阿拉坦五味丸体外抗炎作用机制。方法:以脂多糖诱导RAW264.7细胞建立炎症细胞模型,考察蒙药阿拉坦五味丸对RAW264.7细胞活性以及释放一氧化氮水平的影响。结果:蒙药阿拉坦五味丸显著抑制脂多糖诱导的RAW264.7细胞释放一氧化氮水平(P<0.01)。结论:蒙药阿拉坦五味丸可以通过抑制细胞模型中NO释放水平改善炎症反应。 Objective:To explore the anti-inflammatory mechanism of Mongolian medicine Alantan Wuwei Pill in vitro.Methods:The inflammatory cell model was established by inducing RAW264.7 cells with lipopolysaccharide,and the effect of Mongolian medicine Alatan Wuwei Pills on the level of nitric oxide released by RAW264.7 cells was investigated.Results:The Mongolian medicine Alatan Wuwei Pill significantly inhibited the release of nitric oxide from LPS-induced RAW264.7cells(P<0.01).Conclusion:The Mongolian medicine Alatan Wuwei Pill can improve the inflammatory response by inhibiting the NO release level in the cell model.
作者 阿荣其其格 Avarzed Amgalanbaatar Gerelmaa Enebish Battogtokh Chimeddorj Batnairamdal Chuluun Arongqiqige;Avarzed Amgalanbaatar;Gerelmaa Enebish;Battogtokh Chimeddorj;Batnairamdal Chuluun(Department of Gastroenterology,Affiliated Hospital of Inner Mongolia University for Nationalities,Tongliao 028000,China;Department of Cyber Education,Graduate School,MNUMS,Ulaanbaatar 14210,Mongolia;Department of Microbiology and Infection Prevention Control,School of Biomedicine,MNUMS,Ulaanbaatar 14210,Mongolia;Department of Internal Medicine,International School of Mongolian Medicine,MNUMS,Ulaanbaatar 14210,Mongoli)
出处 《中国民族医药杂志》 2023年第1期25-27,共3页 Journal of Medicine and Pharmacy of Chinese Minorities
关键词 蒙药 阿拉坦五味丸 RAW264.7细胞 抗炎作用 Mongolian medicine Alatan Wuwei Pill RAW264.7 cells anti-inflammatory effect
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