壮医热敏探穴针刺疗法治疗中晚期阴证型发旺的临床观察

Clinical observation of Zhuang medicine heat-sensitive acupoint acupuncture therapy in the treatment of exuberance of Yin syndrome in the middle and late stages

目的:观察壮医热敏探穴针刺疗法治疗中晚期阴证型发旺(类风湿关节炎)的临床疗效及安全性。方法:将64例中晚期阴证型发旺患者随机分为两组,对照组32例给予甲氨蝶呤片、来氟米特片和甲泼尼龙片治疗,观察组32例在西药治疗基础上加用壮医热敏探穴针刺疗法。对比治疗后两组壮医证候积分、临床疗效、压痛关节数(TJC 28)、肿胀关节数(SJC 28)、疾病活动度评分(SDAI)、患者对自身病情活动度的VAS评分(PtGA)、医生对患者病情活动度的VAS评分(PhGA)、健康指数评分(HAQ)、残疾指数评分(HAQ-DI)、血沉(ESR)、C反应蛋白(CRP)、类风湿因子(RF)以及药物不良反应的发生情况。结果:观察组与对照组分别完成31例、32例,观察组总有效率为87.10%(27/31),显著高于对照组的71.88%(23/32)(P<0.05)。观察组证候积分、临床症状、TJC 28、SJC 28、PtGA、PhGA、SDAI、HAQ、HAQ-DI、RF和ESR改善情况均优于对照组,差异均有统计学意义(P<0.05)。两组CRP水平和不良反应发生率差异无统计学意义(P>0.05)。结论:壮医热敏探穴针刺疗法治疗中晚期阴证型发旺疗效确切,可显著改善临床症状,有效缓解关节疼痛,提高生活质量,安全性高,值得临床推广。

Objective:To observe the clinical efficacy and safety of Zhuang medicine heat-sensitive acupuncture acupuncture therapy in the treatment of mid-late negative syndrome hyperthermia(rheumatoid arthritis).Methods:A total of 64 patients with mid-late negative syndrome hyperactivity were randomly divided into two groups,32 patients in the control group were treated with methotrexate tablets,leflunomide tablets and methylprednisolone tablets,and 32 patients in the observation group were treated with western medicine on the basis of treatment.To Zhuang medicine heat-sensitive acupuncture acupuncture therapy.After treatment,the Zhuang doctor syndrome scores,clinical efficacy,number of tender joints(TJC 28),number of swollen joints(SJC 28),disease activity score(SDAI),VAS score of patients’own disease activity(PtGA),Physician’s VAS score(PhGA),health index score(HAQ),disability index score(HAQ-DI),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),rheumatoid factor(RF),and poor medication of patients’disease activity the occurrence of the reaction.Results:The observation group and the control group completed 31 cases and 32 cases respectively.The total effective rate of the observation group was 87.10%(27/31),which was significantly higher than that of the control group,71.88%(23/32)(P<0.05).The improvement of symptom scores,clinical symptoms,TJC 28,SJC 28,Pt GA,PhGA,SDAI,HAQ,HAQ-DI,RF and ESR in the observation group were better than those in the control group,and the differences were statistically significant(P<0.05).There were no significant differences in CRP levels and incidence of adverse reactions between the two groups(P>0.05).Conclusion:Zhuang medicine heat-sensitive acupoint-detecting acupuncture therapy has definite curative effect in the treatment of mid-late negative syndrome hyperactivity,can significantly improve clinical symptoms,effectively relieve joint pain,improve quality of life,and has high safety,which is worthy of clinical promotion.