绝经后子宫内膜癌影响因素分析

ANALYSIS THE INFLUENCING FACTORS OF POSTMENOPAUSAL ENDOMETRIAL CANCER

目的分析绝经后子宫内膜癌的临床特点及影响因素。方法回顾性分析我院2016—2018年282例绝经后子宫内膜病变患者。依据病变性质分为子宫内膜良性病变组和子宫内膜癌组,分析绝经后子宫内膜癌相关影响因素。结果单因素分析结果显示,发病年龄、绝经时长、孕次、糖尿病、子宫内膜厚度、出血等二组差异有统计学意义(P<0.05);多因素Logistic回归分析结果显示,子宫内膜厚度及孕次是子宫内膜癌的影响因素,OR值分别为17.850、4.548。结论子宫内膜显著增厚及孕次是子宫内膜癌的危险因素,年龄越大、绝经时长越长、出血、糖尿病史的存在,有助于子宫内膜癌的初步诊断。

Objective To analyze the clinical characteristics and influencing factors of postmenopausal endometrial carcinoma.Methods Two hundred and eighty-two cases of postmenopausal endometrial disease were analyzed retrospectively.According to the nature of the lesions,the patients were divided into two groups:endometrial benign lesions group and endometrial carcinoma group.Results The results of single factor analysis showed that the age of onset,the length of menopause,the number of pregnancies,diabetes mellitus,endometrial thickness,bleeding and other differences were statistically significant(P<0.05);the results of multivariate logistic regression analysis showed that endometrial thickness and the number of pregnancies were the influencing factors of endometrial cancer,or values were 17.850 and 4.548 respectively.Conclusion Significant endometrial thickening and pregnancy are risk factors for endometrial cancer.The older the age is,the longer the menopause is,and the presence of bleeding and diabetes history is helpful for the preliminary diagnosis of endometrial cancer.