Zinner综合征一例报告并文献复习

Zinner syndrome:A case report and literatures review

目的报告1例Zinner综合征病例,分析其诊治经过,并复习相关文献,提高对于本病的认识。方法回顾性分析1例Zinner综合征病例,患者为18岁男性,因“反复尿频、尿痛、会阴区疼痛不适1年,加重伴发热1 d”入院。经影像学及实验室检查诊断为Zinner综合征。结果入院后给予抗感染治疗7 d后临床症状消失,血常规、降钙素原、C反应蛋白感染指标正常,继续抗感染治疗1周出院。3个月后再次入院复查有轻度尿频,无尿痛症状,检查血常规无异常。行腹腔镜下左侧精囊囊肿切除术,术后病理明确精囊囊肿壁炎症浸润。术后5 d顺利出院。术后6个月内随访尿频、尿痛、会阴区疼痛等不适症状未再发。结论彩超、CT、MRI检查是诊断Zinner综合征的重要手段,病理检查是明确精囊囊肿炎症浸润的依据。急性精囊囊肿感染伴同侧肾缺如、输尿管发育畸形是Zinner综合征的表现形式之一,感染控制后行腹腔镜精囊囊肿切除术安全有效。

Objective To report a case of Zinner syndrome,analyze its diagnosis and treatment,and review relevant literatures to improve the understanding of this disease.Methods A case of Zinner syndrome was retrospectively analyzed.The patient was an 18-year-old male who was admitted to our hospital due to“repeated urinary frequency,dysuria,pain and discomfort in the perineal area for 1 year,aggravation in symptom and fever for 1 day”.Zinner syndrome was diagnosed by imaging and laboratory examination.Results After receiving anti-infection treatment for 7 days,the clinical symptoms disappeared.Blood routine,procalcitonin and CRP infection indexes were normal,and the patient was discharged after continued anti-infection treatment for 1 week.After 3 months,the patient was readmitted to the hospita for re-examination with mild urination frequency,no symptoms of urination pain,and no abnormalities in blood routine examination.Laparoscopic left seminal vesicle cystectomy was performed,and then postoperative pathology confirmed the inflammatory infiltration of the seminal vesicle wall.The patient was discharged from hospital 5 days after the operation.The patient was followed up 6 months after the operation without recurrence of discomfort symptoms such as frequent urination,painful urination and perineal pain.Conclusion Color ultrasound,CT and MRI examinations are important for the diagnosis of Zinner syndrome,and pathological examination is the basis to identify the inflammatory infiltration of seminal vesicle cyst.Acute seminal vesicle cyst infection with ipsilateral renal absence and ureteral dysplasia is one of the manifestations of Zinner syndrome.Laparoscopic seminal vesicle cystectomy after infection control is safe and effective.