2011―2018年重庆多中心恶性肿瘤出院患者生存分析

Survival of Discharged Malignant Tumor Patients from Multi-centers in Chongqing from 2011 to 2018

[目的]对重庆大学附属肿瘤医院牵头的8家医院2011至2018年出院的恶性肿瘤患者的生存情况进行统计分析。[方法]对所有恶性肿瘤患者进行随访,采用寿命表法计算主要恶性肿瘤的观察生存率。采用Log-rank检验比较不同年龄段、不同性别前10位恶性肿瘤的生存率。[结果]该次研究一共纳入60088例恶性肿瘤患者,有效随访49259例,有效随访率81.98%。主要恶性肿瘤患者1~5年生存率分别为76.55%、66.29%、59.88%、56.06%和52.97%。前10位恶性肿瘤患者中,5年生存率最高的是宫颈癌,达到90.70%,其次是乳腺癌,84.08%,生存率最低的是肝癌(14.66%),其次是肺癌(20.43%);经Log-rank检验,不同恶性肿瘤的不同年龄段生存率差异均有统计学意义(P<0.05);不同恶性肿瘤的不同性别生存率相差较大,其中不同性别的肺癌、继发性恶性肿瘤、胃癌差异有统计学意义(P<0.05),其他恶性肿瘤不同性别间的生存率差异均无统计学意义(P>0.05)。[结论]8家单位2011—2018出院的主要恶性肿瘤患者中,肝癌、肺癌、食管癌预后较差,宫颈癌、乳腺癌和鼻咽癌预后相对较好。

[Purpose]To analyze the survival of malignant tumor patients discharged from 8 hospitals in Chongqing from 2011 to 2018.[Methods]A total of 60088 patients with malignant tumors discharged from 8 hospitals in Chongqing were included in the study,among whom 49259 cases were effectively followed up with a follow-up rate of 81.98%.The survival rate was calculated by life table method.Log-rank test was used for testing differences of the survival rates of patients with different gender and age.[Results]The 1-,2-,3-,4-and 5-year survival rates of patients with major malignant tumors were 76.55%,66.29%,59.88%,56.06%,and 52.97%respectively.Among the patients with top 10 malignant tumors,cervical cancer had the highest 5-year survival rate(90.70%),followed by breast cancer(84.08%);and the liver cancer had the lowest survival rate(14.66%),followed by lung cancer(20.43%).Log-rank test showed that there were significant differences in survival of patients with different malignant tumors and in different age groups(P<0.05).There were significant differences in survival rates between male and female patients with lung cancer,secondary malignant tumor and gastric cancer(P<0.05).[Conclusion]Among the patients with main malignant tumor discharged from the 8 hospitals during 2011―2018,those with liver cancer,lung cancer and esophageal cancer had poorer prognosis,and those with cervical cancer,breast cancer and nasopharyngeal cancer hed relatively better prognosis.