2015年云南省肿瘤登记地区恶性肿瘤发病与死亡分析

Cancer Incidence and Mortality of Yunnan Cancer Registration Areas in 2015

[目的]分析2015年云南省肿瘤登记地区恶性肿瘤发病与死亡情况。[方法]收集云南省10个肿瘤登记处上报的2015年恶性肿瘤发病、死亡及人口资料,对数据进行审核和汇总。计算恶性肿瘤发病和死亡的粗率、标化率、累积率(0~74岁)和前10位恶性肿瘤构成,并按地区(城市/农村)、性别和年龄进行分层分析。[结果]2015年云南省肿瘤登记地区登记人口4471006人(城市2959576人,农村1511430人)。恶性肿瘤发病粗率为212.44/10万,中标率为143.77/10万,世标率为139.16/10万,累积率为16.01%。男性发病率高于女性,城市发病率高于农村。恶性肿瘤发病率在40岁后迅速升高,在75~79岁达到高峰。发病前5位的恶性肿瘤依次为肺癌、乳腺癌、结直肠癌、肝癌和宫颈癌。儿童组(0~14岁)常见的恶性肿瘤是白血病和脑及神经系统肿瘤,青壮年组(15~44岁)常见的恶性肿瘤是乳腺癌和甲状腺癌。中年组(45~64岁)常见的恶性肿瘤是乳腺癌和肺癌。老年组(65岁及以上)常见的恶性肿瘤是肺癌和结直肠癌。恶性肿瘤死亡粗率为135.88/10万,中标率为85.55/10万,世标率为84.25/10万,累积率为9.60%。男性死亡率高于女性,农村标化死亡率高于城市。恶性肿瘤死亡率在45岁后迅速升高,在80~84岁达到高峰。死亡前5位的恶性肿瘤依次为肺癌、肝癌、结直肠癌、胃癌和乳腺癌。白血病、脑及神经系统肿瘤是儿童组(0~14岁)最常见的恶性肿瘤死亡原因,乳腺癌和肝癌是青壮年组(15~44岁)最常见的恶性肿瘤死亡原因,肺癌和肝癌是中年组(45~64岁)和老年组(65岁及以上)最常见的恶性肿瘤死亡原因。[结论]云南省恶性肿瘤发病和死亡具本地特征,不同地区、不同性别和年龄别人群癌谱不同。

[Purpose]To analyze the cancer incidence and mortality in Yunnan cancer registration areas in 2015.[Methods]Population and cancer data from 10 local cancer registries of Yunnan province in 2015 were collected and data quality were evaluated according to the criteria of quality control.The crude rates,age-standardized rates(ASR),cumulative rates and the proportion of top 10 cancers were calculated.Incidence and mortality stratified by areas(urban/rural),gender and age groups were also analyzed.[Results]The coverage of population from the cancer registries were 4471006(2959576 in urban and 1511430 in rural).The crude cancer incidence in Yunnan cancer registration areas was 212.44/105.Age-standardized incidence rates adjusted by Chinese standard population(ASIRC)and by world standard population(ASIRW)were 143.77/10~5 and 139.16/10~5,respectively.The cumulative incidence rate(0~74 years old)was 16.01%.Males had higher incidence than females,and the incidence in urban areas was higher than that in rural areas.Cancer incidence increased rapidly after the age of 40 and reached the peak at the age group of 75~79 years.The top five cancer types were lung cancer,breast cancer,colorectal cancer,liver cancer and cervix cancer.The top two common cancers of age group 0~14 years were leukemia and brain tumor.The top two common cancers of age group 15~44 years were breast cancer and thyroid cancer.The top two common cancer of group of 45~64 years were lung cancer and breast cancer.The top two common cancer of age group≥65 years were breast cancer and lung cancer.The crude cancer mortality was 135.88/105.The age-standardized mortality rates adjusted by Chinese standard population(ASMRC)and by world standard population(ASMRW)were 85.55/10~5 and 84.25/10~5,respectively.The cumulative mortality rate(0~74 years old)was 9.60%.Males had higher mortality than females,and the age-standardized mortality rates in urban areas were higher than those in rural areas.Cancer mortality increased rapidly after the age of 45 and reached the peak at the age group of 80~84 years.Lung cancer was the leading cause of cancer death,followed by liver cancer,colorectal cancer,stomach cancer and breast cancer.Leukemia and brain tumor were the top two common causes of cancer death of age group 0~14 years.The top two common cause of cancer death of age group 15~44 years were breast cancer and Liver cancer.The top two common cause of cancer death of age group 45~64 years group and age group≥65 years were lung cancer and liver cancer.[Conclusion]The cancer incidence and mortality of Yunnan registration areas has its local characteristics,and different regions,gender and age groups have different cancer profiles.