浙江省海宁和嘉善肿瘤登记地区恶性肿瘤生存分析

Cancer Survival in Haining and Jiashan Cancer Registry Areas of Zhejiang Province

[目的]分析浙江省海宁和嘉善肿瘤登记地区恶性肿瘤相对生存率。[方法]以海宁市和嘉善县肿瘤登记处收集上报的2003年1月1日至2013年12月31日期间新发的31898例肿瘤登记病例作为研究对象,随访截止日期为2016年4月15日。采用Stata软件strs程序包中EdererⅡ模型计算2003—2006、2007—2010和2011—2014三个不同时期的恶性肿瘤的相对生存率,并对癌种、性别和年龄进行亚组分析。[结果]2003—2006、2007—2010和2011—2014期间,浙江省海宁和嘉善肿瘤登记地区恶性肿瘤5年相对生存率分别为33.6%、38.2%和44.8%,年龄标化的5年相对生存率分别为31.9%、35.6%和37.2%。其中,男性3个时期的5年相对生存率依次为26.9%、28.9%和34.8%,女性依次为43.3%、49.9%和56.8%。胰腺癌、肝癌、肺癌、食管癌和胆囊癌5年相对生存率较低(小于30%),而甲状腺癌、乳腺癌、膀胱癌、肾癌和喉癌等5年相对生存率较高(大于70%)。结直肠癌、子宫体癌、前列腺癌、宫颈癌和脑瘤5年相对生存率增长速度较快,增幅分别为12.8%、13.5%、16.8%、23.6%、38.7%。[结论]浙江省海宁和嘉善肿瘤登记地区恶性肿瘤5年生存率持续上升,以结直肠癌、宫颈癌为代表的癌种防治效果显著,5年相对生存率已达到或接近发达国家水平。

[Purpose]To analyze the population-based cancer relative survival in Haining and Jiashan cancer registry areas of Zhejiang province.[Methods]Cancer incident cases were collected from Haining and Jiashan cancer registries.Patients were diagnosed between January 1,2003 and December 31,2013,with last follow-up information at April 15,2016.Statistical analysis was performed on Stata 15.1 software.Strs package was applied to calculate relative survival by EdererⅡmodel in three periods(2003—2006,2007—2010 and 2011—2014).The data were stratified by cancer type,gender and age group.[Results]The 5-year cancer relative survival was 33.6%for2003—2006,38.2%for 2007—2010 and 44.8%for 2011—2014,with age standardized survival of31.9%,35.6%and 37.2%for corresponding periods.The 5-year cancer relative survival rate in 3 periods was 26.9%,28.9%and 37.2%for males,and 43.3%,49.9%and 56.8%for females.The 5-year relative survival for cancers of the pancreas,liver,lung,esophagus and gallbladder was relatively poor(below 30%);while cancers of the thyroid,breast,bladder,kidney and larynx had fine survival(above 70%).The 5-year relative survival for cancers of the colorectum,uterus,prostate,cervix and brain increased by 12.8%,13.5%,16.8%,23.6%and 38.7%,respectively.[Conclusion]Steady progress in increasing cancer survival has been made over the past few decades in Haining and Jiashan cancer registry areas of Zhejiang province.The 5-year relative survival rates of colorectal and cervical cancers have reached or approached the levels of developed countries in the world.