肺癌转移至口腔颌面部5例分析

Metastasis of lung cancer to oral and maxillofacial region: a report of 5 cases

目的:探讨肺癌口腔颌面部转移的发病机制、鉴别、治疗。方法:收集肺癌转移至口腔颌面部的5例患者,对临床资料进行分析。结果:转移灶均发生于口腔颌面部的软组织,颌面部4例,口腔内1例。其中2例有肺癌的病史,其余3例为首先就诊于口腔科。转移灶病理腺癌4例,鳞癌1例。明确诊断后,5例患者均放弃放化疗,其中仅对症支持治疗的牙龈转移癌患者,1个月后病逝。结论:口腔颌面部转移癌的患者,为肺癌的晚期,要及早诊断治疗,以提高患者生活质量,延长患者的生命。

Objective:To explore the etiology,differential diagnosis and treatment of oral and maxillofacial metastasis of lung cancer.Methods:The clinical data of 5 patients with lung cancer metastasis to oral and maxillofacial region were analyzed.Results:All metastases occurred in the soft tissue of oral and maxillofacial region,including 4 cases in maxillofacial region and 1 case in oral region.Among them,2 cases had a history of lung cancer,and the other 3 cases were first diagnosed in the department of Stomatology.The pathological findings of metastases were adenocarcinoma in 4 cases and squamous cell carcinoma in 1 case.After a definite diagnosis,all the 5 patients gave up chemoradiotherapy,among which the patients with gingival metastasis who only received symptomatic supportive treatment died one-month later.Conclusion:The patients with oral and maxillofacial metastatic cancer are the advanced stage of lung cancer.Early diagnosis and treatment are necessary to improve the quality of life and prolong the life of patients.