摘要
目的探讨低密度脂蛋白胆固醇(LDL-C)联合颈动脉中层厚度(CIMT)检查对冠状动脉粥样硬化性心脏病(CAD)中冠状动脉狭窄≥75%的预测价值。方法选取清远市清新区人民医院2019年1月-2020年12月期间收治的30例冠状动脉狭窄<75%的CAD患者及39例冠状动脉狭窄≥75%的CAD患者作为观察对象,以冠状动脉狭窄<75%者作为对照组,以冠状动脉狭窄≥75%者作为观察组。对比两组LDL-C及CIMT差异,并探讨LDL-C联合CIMT检查对CAD中冠状动脉狭窄≥75%的预测价值。结果①观察组LDL-C及CIMT均高于对照组,差异存在统计学意义(P<0.05)。②LDL-C及CIMT对CAD中冠状动脉狭窄≥75%的最佳预测界值分别为3.50mmol/L及2.30mm。③LDL-C检查、CIMT检查及联合检查对CAD中冠状动脉狭窄≥75%均存在显著的预测价值(P<0.05),以联合检查的预测价值最高。结论在CAD患者冠状动脉狭窄≥75%的筛查中,LDL-C联合CIMT检查具有预测价值,可作为主要的临床预测指标。
Objective To explore predictive value of low density lipoprotein cholesterol(LDL-C)combined with carotid artery middle thickness(CIMT)for coronary artery stenosis≥75%in coronary atherosclerotic heart disease(CAD).Methods The paper chose 30 cases CAD patients with coronary artery stenosis<75%and 39 cases CAD patients with coronary artery stenosis≥75%in Qingyuan City Qingxin District People’s Hospital from January 2019 to December 2020 as observation objects,patients with coronary artery stenosis<75%were included in control group and patients with coronary artery stenosis≥75%in observation group.Difference of LDL-C and CIMT between two groups was compared,predictive value of LDL-C combined with CIMT for coronary stenosis≥75%in CAD was explored.Results①LDL-C and CIMT in observation group was higher than control group(P<0.05).②Best predictive limits of LDL-C and CIMT for coronary stenosis≥75%in CAD were 3.50mmol/l and 2.30mm respectively.③LDL-C examination,CIMT examination and combined examination showed significant predictive value for coronary stenosis≥75%in CAD(P<0.05),combined examination showed the highest predictive value.Conclusion LDL-C combined with CIMT has predictive value in screening patients with coronary stenosis≥75%and can be used as main clinical predictor.
作者
欧文进
欧文岳
徐韵
黎子军
OU Wenjin;OU Wenyue;XU Yun;LI Zijun(Cardiovascular Medicine Department,Qingyuan City Qingxin District People's Hospital,Qingyuan,Guangdong,511500)
出处
《智慧健康》
2022年第27期20-23,共4页
Smart Healthcare
关键词
冠状动脉粥样硬化性心脏病
低密度脂蛋白胆固醇
颈动脉中层厚度
预测价值
Coronary atherosclerotic heart disease
Low density lipoprotein cholesterol
Thickness of middle layer of carotid artery
Predictive value