低密度脂蛋白水平联合颈动脉中层厚度对冠状动脉狭窄的预测价值分析

Predictive Value Analysis of Low Density Lipoprotein Level Combined with Carotid Artery Middle Thickness for Coronary Artery Stenosis

目的探讨低密度脂蛋白胆固醇(LDL-C)联合颈动脉中层厚度(CIMT)检查对冠状动脉粥样硬化性心脏病(CAD)中冠状动脉狭窄≥75%的预测价值。方法选取清远市清新区人民医院2019年1月-2020年12月期间收治的30例冠状动脉狭窄<75%的CAD患者及39例冠状动脉狭窄≥75%的CAD患者作为观察对象,以冠状动脉狭窄<75%者作为对照组,以冠状动脉狭窄≥75%者作为观察组。对比两组LDL-C及CIMT差异,并探讨LDL-C联合CIMT检查对CAD中冠状动脉狭窄≥75%的预测价值。结果①观察组LDL-C及CIMT均高于对照组,差异存在统计学意义(P<0.05)。②LDL-C及CIMT对CAD中冠状动脉狭窄≥75%的最佳预测界值分别为3.50mmol/L及2.30mm。③LDL-C检查、CIMT检查及联合检查对CAD中冠状动脉狭窄≥75%均存在显著的预测价值(P<0.05),以联合检查的预测价值最高。结论在CAD患者冠状动脉狭窄≥75%的筛查中,LDL-C联合CIMT检查具有预测价值,可作为主要的临床预测指标。

Objective To explore predictive value of low density lipoprotein cholesterol(LDL-C)combined with carotid artery middle thickness(CIMT)for coronary artery stenosis≥75%in coronary atherosclerotic heart disease(CAD).Methods The paper chose 30 cases CAD patients with coronary artery stenosis<75%and 39 cases CAD patients with coronary artery stenosis≥75%in Qingyuan City Qingxin District People’s Hospital from January 2019 to December 2020 as observation objects,patients with coronary artery stenosis<75%were included in control group and patients with coronary artery stenosis≥75%in observation group.Difference of LDL-C and CIMT between two groups was compared,predictive value of LDL-C combined with CIMT for coronary stenosis≥75%in CAD was explored.Results①LDL-C and CIMT in observation group was higher than control group(P<0.05).②Best predictive limits of LDL-C and CIMT for coronary stenosis≥75%in CAD were 3.50mmol/l and 2.30mm respectively.③LDL-C examination,CIMT examination and combined examination showed significant predictive value for coronary stenosis≥75%in CAD(P<0.05),combined examination showed the highest predictive value.Conclusion LDL-C combined with CIMT has predictive value in screening patients with coronary stenosis≥75%and can be used as main clinical predictor.