鹦鹉热衣原体肺炎5例临床特征分析及其诊治

Analysis of Clinical Features and Diagnosis and Treatment of 5 Cases of Chlamydia Psittacosis Pneumonia

目的将5例鹦鹉热衣原体肺炎疾病患者视为本研究观察者,对其临床特征展开分析,回顾其临床诊断治疗资料,进而增加对此疾病的临床认知。方法选取北京大学首钢医院及潞河医院在2020年1月-2022年1月所治疗的鹦鹉热衣原体肺炎5例患者,回顾其临床资料,分析患者疾病临床特征以及诊治方式。结果患者临床症状主要是发热以及干咳,同时大部分都有鸟类接触经历,通过对患者采取宏基因二代测序技术进行临床诊断出患者存在鹦鹉热衣原体核酸序列情况,在此基础上联合各方面表现进而确诊。结论临床对于鹦鹉热衣原体肺炎疾病诊断过程中使用宏基因二代测序技术能够迅速且灵敏的诊断出是否存在鹦鹉热衣原体序列,并且对于其他隐藏病原体进行鉴别。

Objective By taking 5 patients with Chlamydia psittacosis pneumonia as the observers of this study,analyzing their clinical characteristics and reviewing their clinical diagnosis and treatment data,so as to increase the clinical cognition of this disease.Methods Five patients with Chlamydia psittaci pneumonia treated in our hospital from January 2020 to January 2022 were selected,their clinical data were retrospectively analyzed,and the clinical characteristics and diagnosis and treatment methods of the patients were analyzed.Results The clinical symptoms of the patients were mainly fever and cough,and most of them also had contact with birds or poultry.The patients were clinically diagnosed with the nucleic acid sequence of Chlamydia psittaci by using the next-generation sequencing technology of metagenomic.All aspects of the clinical features and diagnosis and treatment methods were analyzed.Conclusion The use of metagenomic next-generation sequencing technology in the clinical diagnosis of Chlamydia psittacosis pneumonia disease can quickly and sensitively diagnose the presence of Chlamydia psittacosis sequences,and it also has an identification effect on other hidden pathogens.