俯卧位无创通气在呼吸窘迫综合征治疗中的临床效果观察

Clinical Observation of Noninvasive Ventilation in Prone Position in the Treatment of Respiratory Distress Syndrome

目的分析俯卧位无创通气在呼吸窘迫综合征治疗中的临床效果。方法回顾分析我院2017年2月至2021年5月收治的呼吸窘迫综合征患者135例,按其治疗方式分组,其中82例接受俯卧位无创通气治疗(观察组),另53例接受仰卧位无创通气治疗(对照组),比较治疗效果,如血气指标、心肺功能、ICU时间、机械通气时间等。结果比较氧合指数,治疗前组间数据差异无统计学意义(P>0.05),治疗2d、4d、8d后,观察组氧合指数高于对照组,组间数据差异有统计学意义(P<0.05),比较治疗中各项监测指标,治疗前组间数据差异无统计学意义(P>0.05),治疗后,观察组LAP高于对照组,Lac、Pplat低于对照组,组间数据差异有统计学意义(P<0.05),MAP、APP数据差异无统计学意义(P>0.05)。观察组住院时间、ICU救治时间、带管时间、呼吸机使用时间低于对照组,组间数据差异有统计学意义(P<0.05)。结论呼吸窘迫综合征患者接受俯卧位无创通气治疗,可显著改善其氧合功能和肺功能,对疾病恢复有促进效果。

Objective To analyze the clinical effect of non-invasive ventilation in prone position in the treatment of respiratory distress syndrome.Methods A retrospective analysis was conducted on 135 patients with respiratory distress syndrome admitted to our hospital from February 2017 to May 2021.The patients were grouped according to their treatment methods,among whom 82 patients received non-invasive ventilation in the prone position(observation group)and 53 patients received non-invasive ventilation in the supine position(control group).The therapeutic effects were compared,such as blood gas index,cardiopulmonary function,ICU time,mechanical ventilation time and so on.Results Comparison of oxygenation index showed no statistically significant difference between the groups before treatment(P>0.05).After treatment for 2d,4d and 8d,the oxygenation index of the observation group was higher than that of the control group(P<0.05),and comparison of monitoring indexes during treatment showed no statistically significant difference between the groups before treatment(P>0.05).LAP of observation group was higher than that of the control group,LAC and PPLAT of observation group were lower than those of the control group,and the data between groups were statistically significant(P<0.05).MAP and APP data had no statistically significant difference(P>0.05).The duration of hospitalization,ICU treatment,catheter insertion and ventilator use in the observation group were lower than those in the control group,and the data between groups were statistically significant(P<0.05).Conclusion Non-invasive ventilation in prone position can significantly improve oxygenation and lung function in patients with respiratory distress syndrome,and promote the recovery of the disease.