对急性加重期慢阻肺采用布地奈德辅助复方异丙托溴铵治疗的效果观察

Effect Observation of Budesonide Combined With Compound Ipratropium Bromide in Treatment of Acute Exacerbation COPD

目的分析急性加重期慢阻肺采用布地奈德辅助复方异丙托溴铵治疗的效果。方法选取2018年5月-2020年4月在武威市凉州医院诊疗的50例急性加重期慢阻患者作为研究样本,依据随机原则将其划分2组,设为研究组(25例)和参照组(25例)。参照组患者接受复方异丙托溴铵治疗,研究组患者接受布地奈德辅助复方异丙托溴铵治疗,对比治疗后的临床疗效。结果研究组治疗总有效率(96.00%)显著高于参照组(72.00%),P<0.05。研究组FVC、FEV_(1)、PaO_(2)、PaCO_(2)等指标改善优于参照组,P<0.05。结论急性加重期慢阻肺采用布地奈德辅助复方异丙托溴铵治疗可获取显著的临床疗效,同时有效改善患者的呼吸功能和免疫功能,值得在临床上进一步推广和实践。

Objective To analyze effect of budesonide combined with compound ipratropium bromide in treatment of acute exacerbation COPD.Methods The paper chose 50 patients with acute exacerbation chronic obstructive disease treated in our hospital from May 2018 to April 2020 as research samples,and divided them into two groups according to randomization principle,namely research group(25 cases)and reference group(25 cases).Reference group was treated with compound ipratropium bromide,study group with budesonide assisted with compound ipratropium bromide.Clinical effect was compared between two groups.Results Total effective rate of study group(96.00%)was significantly higher than reference group(72.00%),P<0.05.Improvement of FVC,FEV_(1),PaO_(2)and PaCO_(2) in study group was better than reference group(P<0.05).Conclusion Budesonide combined with compound ipratropium bromide can obtain significant clinical curative effect in treatment of COPD in acute exacerbation,improve respiratory function and immune function of patients effectively,which is worthy of further promotion and practice in clinical practice.