冠心舒通胶囊联合西药治疗冠心病稳定型心绞痛的临床疗效及对血脂、hs-CRP的影响研究

The Clinical Efficacy of Coronary Heart Sultan Capsule combined with Western Medicine to Treat Coronary Heart Disease Stable Angina and its Effect on Blood Lipids and hs-CRP

目的观察冠心舒通胶囊联合西药治疗冠心病稳定型心绞痛的临床疗效及对血脂、hs-CRP的影响。方法将我院近期(2016年7月至2020年5月时期)收治冠心病稳定型心绞痛为诊断并以常规西药治疗的300例患者,采取以随机数字法分组每组各150例,其中150例不做任何其他联合治疗设置为对照组,而另150例患者接受联合冠心舒通胶囊治疗设置为实验组。疗程结束后将两组治疗前后血脂、炎性因子水平及临床疗效比较。结果两组治疗前血脂四项水平差异无意义(P>0.05)。治疗后血脂四项水平中TC、TG、LDL水平较治疗前明显的降低,而HDL水平则明显的升高,其中实验组TC、TG、LDL水平低于对照组,而HDL水平高于对照组,差异有意义(P<0.05)。两组治疗前炎性指标水平差异无意义(P>0.05)。治疗后炎性指标水平中hs-CRP、IL-6水平较治疗前明显的降低,其中实验组hs-CRP、IL-6水平低于对照组,差异有意义(P<0.05)。患者在疗程内均接受有效的治疗,用药依从性良好,实验组患者治疗总有效率(89.33%)高于对照组(64.67%),差异有意义(P<0.05)。结论在冠心病稳定型心绞痛患者的治疗中,采取冠心舒通胶囊联合西药治疗可明显的降低患者治疗后的血脂与血清炎性因子水平,相对于仅采取西药治疗的患者,获得较高的治疗总有效率,效果理想。

Objective To observe the clinical efficacy of coronary heart thyropoietre in the treatment of coronary heart disease-stabilized angina and its effect on blood lipids and hs-CRP.Methods The recent treatment of coronary heart disease-stabilized angina in our hospital (July 2016-May 2020 period) was diagnosed and treated with conventional Western medicine in 300 patients,150 cases were grouped in random numbers,of which 150 patients did not do any other combined therapy set to the control group,while 150 patients received joint coronary throbbing capsule therapy as an experimental group.After the course of treatment,the level of blood lipids,inflammatory factors and clinical efficacy were compared between the two groups before and after treatment.Results The differences in blood lipid levels were meaningless in the two groups before treatment(P>0.05).The levels of TC,TG and LDL were significantly lower than before treatment in the four levels of lipids after treatment,while the levels of HDL were significantly higher,with the levels of TC,TG and LDL in the experimental group lower than those in the control group,while the HDL levels were higher than those in the control group,and the difference was Meaningful(P<0.05).The difference in pre-treatment inflammatory index levels between the two groups was meaningless(P>0.05).The levels of hs-CRP and IL-6 in the post-treatment inflammatory index were significantly lower than before treatment,where in the levels of hs-CRP and IL-6 in the experimental group were lower than those in the control group,and the difference was meaningful(P>0.05).Patients received effective treatment during the course of treatment,the drug compliance was good,the total treatment efficiency of patients in the experimental group (89.33%) was higher than that of the control group (64.67%),and the difference was meaningful(P<0.05).Conclusion In the treatment of patients with coronary heart disease stable angina,the treatment of coronary heart throbbing capsule combined with Western medicine can significantly reduce the level of blood lipids and serum inflammatory factors after treatment,compared with patients treated only with Western medicine,to obtain higher treatment efficiency and ideal effect.