慢阻肺急性加重伴合并症病人关于糖皮质激素使用情况的分析

Analysis of the Use of Glucocorticoids in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease

目的分析比较本院慢阻肺急性加重伴高血压病人糖皮质激素不同使用情况下的临床效果。方法收集本院慢阻肺急性加重伴高血压病人使用的糖皮质的不同途径进行分类,全身使用糖皮质激素>5 d为A组,全身使用糖皮质>5 d伴停用后改吸入用糖皮质激素为B组,全部吸入糖皮质激素>5 d为C组,分别比较使用疗效,对肺功能检查结果、生化指标及其血压情况、住院时间及其副作用进行评价。结果A、B、C三组治疗后肺功能有统计学意义,PaO2经治疗后有统计学意义,PaCO2治疗前后无统计学意义,血压治疗前后没有统计学意义。结论运用激素治疗慢阻肺急性加重伴高血压病人是把双刃剑,什么样的情况下使用,使用多久,就要求医生更加全面地对患者进行评估,谨慎选择合适的治疗方案,改善患者生活质量,降低发病次数,增加生存的空间。

Objective To analyze and compare the clinical effects of glucocorticoid use in patients with acute exacerbation of copd with hypertension in our hospital.Methods Collected in our hospital copd exacerbations with hypertensive patients using different ways to classify of glucocorticoid,divided into general use of glucocorticoid>5 days group,group A systemic use of glucocorticoid>5 days with discontinuation change the inhaled corticosteroids group B,all inhaled corticosteroids>5 days group,group C were compared using curative effect,the pulmonary function test results,the biochemical indicators and their blood pressure,length of hospital stay and its side effects were evaluated.Results Lung function in group A,B and C was statistically significant after treatment,PaO2 after treatment,PaCO2 before and after treatment,and blood pressure before and after treatment were not statistically significant.Conclusion It is a double-edged sword to use hormone to treat patients with acute exacerbation of COPD and hypertension.Under what circumstances and for how long,doctors are required to evaluate the patients more comprehensively,carefully choose the appropriate treatment scheme,improve the quality of life of patients,reduce the number of attacks,and increase the living space.