硫酸镁结合酚妥拉明治疗妊高症的效果分析

Effect of Magnesium Sulfate combined with Phentolamine in the Treatment of Pregnancy-induced Hypertension

目的分析妊高症采取硫酸镁联合酚妥拉明治疗的效果。方法选取自2017年10月至2019年10月两年期间,在我院接受治疗的妊高症患者89例。依据随机分配的原则将89例患者分为观察组和对照组,其中观察组患者数量为44例、对照组患者数量为45例,对照组患者采用酚妥拉明进行单独治疗,观察组患者采用硫酸镁与酚妥拉明联合的方式进行治疗,对比两组患者的治疗效果、妊娠结局以及治疗前后血压变化情况。结果观察组患者的治疗有效率明显高于对照组患者的治疗有效率,对比后差异具有统计学意义(x2=6.7656,P=0.0093);观察组患者的妊娠结局明显优于对照组患者的妊娠结局,对比后差异具有统计学意义(x2=4.2322,P=0.0397);在接受治疗之前,两组患者的平均收缩压和平均舒张压均没有明显差异,组间不存在统计学意义,P>0.05;在接受不同治疗方法之后,两组患者的收缩压、舒张压两项指标水平都有所降低,且观察组患者治疗后的收缩压和舒张压明显低于对照组,对比后差异同样具有统计学意义(t1=11.8958,P1=0.0000;t2=5.7822,P2=0.0000)。结论硫酸镁联合酚妥拉明治疗妊高症效果显著,可降低不良妊娠结局,保证母婴健康,值得在临床当中推广和应用。

Objective To analyze the effect of magnesium sulfate combined with phentolamine on pregnancy-induced hypertension.Methods First of all,the scope of sample selection is determined for the patients with pregnancy induced hypertension in our hospital,and then the sample selection time is determined.The sample number is 89 during the two years from October 2017 to October 2019.According to the principle of random distribution,89 patients were divided into the observation group and the control group.The number of patients in the observation group was 44,and the number of patients in the control group was 45.The patients in the control group were treated with phentolamine alone,while the patients in the observation group were treated with magnesium sulfate and phentolamine.The treatment effect,pregnancy outcome and blood pressure changes of the two groups were compared situation.Results The effective rate of the observation group was significantly higher than that of the control group,the difference was statistically significant(x~2=6.7656,P=0.0093),the pregnancy outcome of the observation group was significantly better than that of the control group(x~2=4.2322,P=0.0397).Before treatment,there was no significant difference in mean systolic blood pressure and mean diastolic blood pressure between the two groups,and there was no statistical significance between the two groups,P>0.05.After receiving different treatment methods,the systolic blood pressure and diastolic blood pressure of the two groups were decreased,and the systolic and diastolic blood pressure of the observation group was significantly lower than that of the control group,and the difference was also statistically significant(t1=11.8958,P1=0.0000;t2=5.7822,P2=0.0000).Conclusion Magnesium sulfate combined with phentolamine has a significant effect on the treatment of pregnancy-induced hypertension,which can reduce adverse pregnancy outcomes and ensure the health of mothers and infants,and is worthy of application.