阿替普酶联合利伐沙班应用于急性肺栓塞治疗中的临床效果分析

Clinical Analysis of Alteplase Combined with Rivaroxaban in the Treatment of Acute Pulmonary Embolism

目的分析急性肺栓塞应用阿替普酶联合利伐沙班治疗的临床效果。方法选取30例急性肺栓塞病人作为研究对象,将病人分为实验组和对照组。对照组给予利伐沙班治疗,实验组选择阿替普酶联合利伐沙班治疗,对比两组病人的临床治疗效果和不良事件发生情况。结果实验组病人的治疗总有效率93.33%高于对照组80.00%,差异较大(P<0.05);实验组病人不良事件发生率为13.33%,对照组不良事件发生率为20.00%,两组对比无显著差别(P>0.05)。结论对急性肺栓塞病人应用阿替普酶和利伐沙班联合治疗可有效提高临床治疗效果,具有较好的抗凝和溶栓效果,从而促进肺功能的恢复,且无严重不良事件发生,值得临床推广。

Objective To analyze the clinical effect of acute pulmonary embolism treated with Alteplase and Rivaroxaban.Methods Thirty patients with acute pulmonary embolism were divided into experimental group and control group.The control group was treated with Rivaroxaban,and the experimental group was treated with Alteplase and Rivaroxaban.The clinical effect and adverse events of the two groups were compared.Results The total effective rate of the experimental group was 93.33%higher than that of the control group(80.00%)(P<0.05).The incidence of adverse events in the experimental group was 13.33%,the incidence of adverse events in the control group was 20.00%,there was no significant difference between the two groups(P>0.05).Conclusion The combination of Alteplase and Rivaroxaban can effectively improve the clinical therapeutic effect,have better anticoagulation and thrombolysis effect,thus promote the recovery of pulmonary function,and have no serious adverse events,which is worthy of clinical promotion.