血浆D二聚体水平在急性冠脉综合征、急性肺栓塞、主动脉夹层鉴别诊断中的应用价值研究

The Value of Plasma D-dimer in the Differential Diagnosis of Acute Coronary Syndrome,Acute Pulmonary Embolism and Aortic Dissection

目的研究血浆D二聚体水平(DD)被应用到急性冠脉综合征(ACS)、急性肺栓塞(APE)、主动脉夹层(AD)中的诊断作用与效果。方法在2017年11月直到2019年10月这一时间段中,择选出我院收入的192例胸痛住院ACS病例、19例APE病例、8例AD病例,把其作为ACS组、APE组、AD组,在ACS组中,ST段抬高型心肌梗死(STEMI)、非ST段抬高型心肌梗死(NSTEMI)、不稳定型心绞痛(UAP)患者依次是128例、39例、25例,把其作为STEMI组、NSTEMI组、UAP组;另外,在同一时间段中,择选出我院收入的31例进行冠脉造影的正常体检者,把其作为对照组,对所有受检对象进行DD检测,观察比较其最终的结果。结果在检测后,对于DD,APE组、AD组较ACS组、对照组更高(P<0.05);而ACS组对比对照组,没有显著性的差异(P>0.05);而STEMI组、NSTEMI组、UAP组对比对照组,没有显著性的差异(P>0.05)。结论DD检测被应用到诊断ACS、APE、AD中,能够得到更为满意的效果。

Objective To study the diagnostic effect and effect of plasma D-dimer level(DD)on acute coronary syndrome(ACS),acute pulmonary embolism(APE),and aortic dissection(AD).Methods During the period from November 2017 to October 2019,192 cases of chest pain hospitalized ACS cases,19 cases of APE cases,and 8 cases of AD cases were selected from our hospital as the ACS group and the APE group.AD group,ST segment elevation myocardial infarction(STEMI),Non-ST-segment elevation myocardial infarction(NSTEMI)and unstable angina pectoris(UAP)were 128,39,and 25 patients in turn,and they were used as the STEMI group,NSTEMI group,and UAP group,in addition,during the same time period,Thirty-one normal patients who underwent coronary angiography were selected from our hospital.They were selected as the control group,and all subjects were tested for DD.The final results were observed and compared.Results After detection,the DD,APE and AD groups were higher than the ACS and control groups(P<0.05);the ACS group had no significant difference compared with the control group(P>0.05);There was no significant difference between the NSTEMI group and the UAP group compared with the control group(P>0.05).Conclusion The DD test is applied to the diagnosis of ACS,APE,AD,and can achieve more satisfactory results.