急性ST段抬高型心肌梗死溶栓后早期介入治疗的临床观察

Early Interventional Therapy after Thrombolysis in Patients with Acute ST Segment Elevation Myocardial Infarction

目的比对研究先溶栓后行早期经皮冠状动脉介入治疗(PCI)对急性ST段抬高型心肌梗死(STEMI)患者的治疗效果。方法回顾性分析2017年1月至2019年12月在我院接受治疗的ST段抬高型心肌梗死患者200例,随机将患者分为实验组(100例,行先溶栓再接受PCI治疗)、比对组(100例,直接行PCI治疗)。观察无复流/慢血流发生情况、MACE(术后主要心血管不良事件)发生率、CK-MB峰值。结果实验组患者CK-MB峰值更低,无复流/慢血流发生人数更少,P<0.05;MACE发生率,P>0.05。结论先溶栓再行PCI对治疗STENT患者效果更好,可以进行临床推广实验。

Objective To compare the therapeutic effect of early percutaneous coronary intervention(PCI)after thrombolysis on patients with acute ST segment elevation myocardial infarction(STEMI).Methods Two hundred patients with ST segment elevation myocardial infarction who were treated in our hospital from January 2017 to December 2019 were analyzed retrospectively.The patients were randomly divided into experimental group(100 cases,thrombolysis before PCI)and control group(100 cases,PCI treatment directly).No reflow/slow blood flow,MACE(major cardiovascular adverse events)and peak CK-MB were observed.Results In the experimental group,the peak value of CK-MB was lower,the number of patients without reflow/slow blood flow was less,P<0.05.The incidence of MACE,P>0.05.Conclusion Thrombolysis followed by PCI is more effective in treating patients with STENT and can be used in clinical trials.