西格列汀+地特胰岛素治疗老年2型糖尿病的临床疗效分析

Clinical Effect Analysis of Sitagliptin + Insulin Detemir in Treatment of Elderly Type 2 Diabetes

目的研究西格列汀+地特胰岛素治疗老年2型糖尿病的临床疗效。方法选择接受治疗的老年2型糖尿病患者作为本次研究对象,根据其入院顺序对其进行分组,将100例老年2型糖尿病患者进行分组,主要包括两组,其中观察组实施西格列汀+地特胰岛素治疗;对照组实施瑞格列奈+地特胰岛素治疗,将两组各项血糖指标、低血糖发生率进行对比。结果观察组老年2型糖尿病患者FPG、2 hPG、HbAlc、胰岛素用量各项指标与对照组相比较,具有明显优势(P<0.05)。观察组患者低血糖发生率显著低于对照组,P<0.05。结论西格列汀+地特胰岛素治疗老年2型糖尿病的临床疗效十分显著,且能降低患者低血糖发生率,值得研究和推广。

Objective to study clinical effect of sitagliptin+insulin detemir in treatment of elderly type 2 diabetes.Methods choose elderly type 2 diabetic patients received treatment as study objects,divide 100 cases into two groups according to admission sequence,observation group was treated with sitagliptin+insulin detemir treatment;and control group with repaglinide+insulin detemir.Compare blood glucose indexes and incidence of hypoglycemia between two groups.Results FPG(6.34±1.23)mmol/L,2 hPG(8.34±1.02)mmol/L,HbA1 c(6.45±1.01)%,insulin dosage(25.34±1.09)kg/m2 of elderly type 2 diabetes patients in observation group has more obvious advantages than control group,(P<0.05).Incidence of hypoglycemia in observation group was 2.00%,significantly lower than control group,24.00%,P<0.05.Conclusion sitagliptin+insulin detemir can achieve significant clinical effect in treatment of elderly type 2 diabetes,reduce incidence of hypoglycemia of patients,which is worthy of research and promotion.