小儿肺炎支原体肺炎合并全身炎症反应综合征时超敏CRP、PCT、WBC变化及临床意义研究

Changes of CRP, PCT and WBC in Children with Mycoplasma Pneumoniae Pneumonia and Systemic Inflammatory Response Syndrome and Their Clinical Significance

目的探讨小儿肺炎支原体肺炎合并全身炎症反应综合征时超敏CRP、PCT、WBC变化及临床意义。方法选取我院儿科于2014年4月至2019年4月所收治的186例小儿肺炎支原体肺炎患者为研究对象,依是否合并全身炎症反应分为合并组和单一组,对所有患儿行血清检测,比较各组患儿治疗前后的超敏CRP、PCT与WBC水平变化情况。结果合并组患儿治疗前的超敏CRP、PCT与WBC水平较单一组均明显更高(P<0.05),经治疗均有所下降,但合并组治疗后的超敏CRP、PCT与WBC水平较单一组仍明显更高(P<0.05)。结论小儿肺炎支原体肺炎合并全身炎症反应综合征时超敏CRP、PCT与WBC水平会发生显著变化,检测患儿超敏CRP、PCT与WBC有助于判断疾病的轻重,预估临床治疗效果与预后。

Objective To investigate the changes of CRP,PCT and WBC in children with Mycoplasma pneumoniae pneumonia and systemic inflammatory response syndrome.Methods One hundred and eighty-six children with Mycoplasma pneumoniae pneumonia admitted in our hospital from April 2014 to April 2019 were selected as the study objects.According to whether there was systemic inflammatory reaction,they were divided into two groups:combined group and single group.Serum tests were performed on all children.The changes of the levels of hypersensitive CRP,PCT and WBC were compared before and after treatment.Results The levels of high sensitive CRP,PCT and WBC in the combined group were significantly higher than those in the single group(P<0.05),but the levels of high sensitive CRP,PCT and WBC in the combined group were still significantly higher than those in the single group(P<0.05).Conclusion The levels of hypersensitive CRP,PCT and WBC in children with Mycoplasma pneumoniae pneumonia complicated with systemic inflammatory response syndrome will change significantly.Detection of hypersensitive CRP,PCT and WBC in children can help to judge the severity of the disease and predict the clinical therapeutic effect and prognosis.