评价腹腔镜下子宫肌瘤剔除术对子宫肌瘤患者卵巢功能、氧化损伤及舒适度的影响

Effect Evaluation of Laparoscopic Myomectomy on Ovarian Function, Oxidative Damage and Comfort in Hysteromyoma Patients

目的探究子宫肌瘤患者行腹腔镜下子宫肌瘤剔除术的临床效果。方法对我院子宫肌瘤患者的60例病例随机抽取,于2018年6月至2019年6月收治,对照组30例采取传统开腹子宫肌瘤剔除术,观察组30例采用腹腔镜下子宫肌瘤剔除术,对比相关临床指标。结果观察组E2(雌二醇)、FSH(促卵泡成熟素)、LH(促黄体生成素)等卵巢功能指标均低于对照组,具有统计学意义(P<0.05);观察组IL-6(白细胞介素-6)、IL-8(白细胞介素-8)、TNF-a(肿瘤坏死因子-a)等氧化应激指标均低于对照组,具有统计学意义(P<0.05)。结论腹腔镜下子宫肌瘤剔除术应用于子宫肌瘤患者治疗中,对卵巢功能、血清性激素的影响较小,舒适度、安全性更高。

Objective to explore clinical effect of laparoscopic myomectomy in hysteromyoma patients.Methods choose 60 cases hysteromyoma patients in our hospital from June 2018 to June 2019 randomly.30 cases in control group were treated with traditional open hysteromyomectomy,30 cases in observation group with laparoscopic hysteromyomectomy.Compare related clinical indicators.Results ovarian function indexes of E2(estradiol),FSH(follicle stimulating hormone),LH(luteinizing hormone)in observation group were lower than control group(P<0.05);oxidative stress indexes of IL-6(IL-6),IL-8(IL-8),TNF-a(tumor necrosis factor-a)in observation group were lower than control group,with statistical significance,(P<0.05).Conclusion laparoscopic myomectomy has less effect on ovarian function and serum hormone in treatment of hysteromyoma patients,with higher comfort and safety.