翼状胬肉实施角膜缘修复术辅以妥布霉素地塞米松的治疗研究

Research on Limbal Repair with Tobramycin and Dexamethasone in Treatment of Pterygium

目的研究翼状胬肉实施角膜缘修复术辅以妥布霉素地塞米松的治疗效果。方法研究组采用胬肉切除术联合角膜缘修复术,术后辅以妥布霉素地塞米松滴眼。对照组:本组采取胬肉切除术并羊膜移植术,术后辅以妥布霉素地塞米松滴眼。对比两组手术时间、角膜上皮愈合时间,异物感显著时间及异物感有限时间。对比两组术后并发症发生率及胬肉复发率。结果研究组手术时间、角膜上皮愈合时间,异物感显著时间及异物感有限时间显著短于对照组(P<0.05)。研究组术后并发症发生率显著低于对照组(P<0.05)。两组胬肉复发率无显著差异(P>0.05)。结论翼状胬肉实施角膜缘修复术辅以妥布霉素地塞米松治疗,其术式效果便捷且远期效果可靠,促进患者更快恢复,术后并发症更少。

Objective to study effect of limbal repair combined with tobramycin and dexamethasone on pterygium.Methods study group was treated with pterygium resection combined with limbal repair,and control group with pterygium resection and amniotic membrane transplantation.Compare operation time,corneal epithelial healing time,significant time of foreign body sensation and limited time of foreign body sensation between two groups.And compare postoperative complications incidence and recurrence rate of pterygium between two groups.Results operation time,corneal epithelial healing time,significant time of foreign body sensation and limited time of foreign body sensation in study group was significantly shorter than control group(P<0.05).Incidence of postoperative complications in study group was significantly lower than control group(P<0.05).Pterygium recurrence rate showed no significant difference between two groups(P>0.05).Conclusion limbal repair combined with tobramycin and dexamethasone can achieve convenient and reliable effect for pterygium in the long term,accelerate recovery of patients with postoperative complications.