摘要
目的探讨硫糖铝混悬凝胶联合艾司奥美拉唑治疗2型糖尿病合并消化性溃疡临床疗效。方法92例确诊为2型糖尿病合并消化性溃疡患者,随机分为治疗组和对照组,在抗幽门螺旋杆菌的基础上,对照组给予艾司奥美拉唑20 mg/次,2次/d治疗,疗程为4周,治疗组在对照组的基础上加用硫糖铝混悬凝胶,5 mL/次,2次/d,疗程为4周。结果治疗组消化性溃疡临床症状总有效率为95.8%,内镜下改善率95.8%,均明显优于对照组(P<0.05)。结论硫糖铝混悬凝胶联合艾司奥美拉唑治疗2型糖尿病合并消化性溃疡疗效确切,副作用少。
Objective To investigate the clinical effect of sucralfate suspension gel combined with esomeprazole in the treatment of type 2 diabetes mellitus complicated with peptic ulcer.Methods Ninety-two patients diagnosed as type 2 diabetes and peptic ulcer were randomly divided into treatment group and control group.On the basis of anti helicobacter pylori,the control group was given omeprazole 20 mg/times,2 times/d treatment,the treatment course was 4 weeks,the treatment group was added sucralfate suspensoid gel,5 mL/times,2 times/d on the basis of the control group,the treatment course was 4 weeks.Results The total effective rate of clinical symptoms of peptic ulcer in the treatment group was 95.8%,and the improvement rate under endoscopy was 95.8%,which was significantly better than that in the control group(P<0.05).Conclusion The effect of sucralfate suspensoid gel combined with esomeprazole in the treatment of T2 DM with peptic ulcer is accurate and has few side effects.
作者
雷浩
韦明勇
彭薛
吴军
刘海英
杨艳
张珊
舒巧
LEI Hao;WEI Ming-yong;PENG Xue;WU Jun;LIU Hai-ying;YANG Yan;ZHANG Shan;SHU Qiao(Sichuan Science City Hospital,Mianyang,Sichuan 621000)
出处
《智慧健康》
2020年第2期142-143,145,共3页
Smart Healthcare