肺炎支原体特异性IgG、IgM半定量检测在小儿MP感染中的应用

Application of Specific IgG, IgM Semi-quantitative Detection of Mycoplasma Pneumoniae in Children with MP Infection

目的探究小儿MP感染检查中肺炎支原体特异性IgG、IgM半定量检测的应用效果。方法将我院2016年2月至2018年3月收治的1189例MP感染患儿作为研究对象,所有患儿均进行肺炎支原体特异性IgG、IgM半定量检测,分别对比不同年龄段患儿MP-IgG、MP-IgM半定量检测情况,并分别对比双份血清MP检测结果。结果不同年龄段患儿MP-IgG、MP-IgM半定量检测结果中检出率最高为的为7-12岁,其次为3-6岁,1189患儿双份血清经MP-IgG、MP-IgM半定量检测均为MP感染阳性的有206例,占比为17.33%,检测均为MP感染阴性的有831例,占比为69.89%,第一份血清检测为阳性第二份血清检测为阴性的有43例,占比为3.62%,第一份血清检测为阴性第二份血清检测为阳性的有109例,占比为9.17%,组间差异对比显著,有统计学意义(P<0.05)。结论 MP感染是小儿呼吸道感染中较为常见的一种,且年龄越大感染率越高,肺炎支原体特异性IgG、IgM半定量检测能够有效提升临床检测准确率,对于临床诊断及治疗效果的提升均有非常重要的作用。

Objective To explore the application of specific IgG and IgM in the detection of MP infection in children. Methods A total of 1189 cases of MP-infected children from February 2016 to March 2018 were treated as subjects, and all the children with MP-IgG and MP-IgM were compared with MP-IgG and MP-IgM in different age groups. And the results of the two-part serum MP were compared. Results The highest detection rate of MP-IgG,MPIgM was 7-12 years old, followed by 3-6 years old. 1189 of the children were positive for MP infection by MP-IgG,MPIgM semi-quantitative test, accounting for 17.33%. 831 cases(69.89%) were negative for MP infection, and 43 cases were negative for the first serum. The proportion was 3.62%. 109 cases(9.17%) were negative in the first serum test and positive in the second serum test. There was significant difference between the two groups(P<0.05).Conclusion MP infection is a common kind of respiratory tract infection in children, and the older the infection rate is, the higher the infection rate is. The semi-quantitative detection of mycoplasma pneumoniae specific IgG,IgM can effectively improve the accuracy of clinical detection, which plays a very important role in clinical diagnosis and treatment.