温灸疗法对宫颈癌腹腔镜手术后患者疗效及免疫功能的影响

Effect of warm moxibustion on the efficacy and immune function of patients with cervical cancer after laparoscopic surgery

目的探究温灸疗法对宫颈癌腹腔镜下手术后康复期患者临床结局及免疫功能的影响。方法选取2016年8月~2018年7月宁波市妇女儿童医院收治的宫颈癌腹腔镜下手术后康复期的患者76例,采用随机数表法将患者分为对照组和试验组,每组38例,其中试验组采用温灸疗法,对照组采用传统常规疗法,统计两组患者的术后肛门排气时间、住院时间以及免疫系统中T细胞亚群(CD3+、CD4+、CD8+)水平和免疫球蛋白(IgA、IgG、IgM)水平在术后1、7 d的变化。结果试验组患者术后肛门排气以及住院时间均少于对照组,差异有统计学意义(t=0.020,0.010,P<0.05)。术后两组患者的T细胞亚群水平和免疫球蛋白水平较术前均有下降趋势,术后1 d试验组患者的CD3+、CD4+、CD8+下降程度均低于对照组(t=0.020、0.002、0.005;P<0.05),术后7 d,两组患者的水平均有一定的回升,其中试验组患者已接近正常水平,差异均有统计学意义(t=0.020、0.033、0.010;P<0.05);术后1 d,试验组患者的免疫球蛋白IgA、IgG、IgM水平下降程度均明显低于对照组(t=0.020、0.002、0.001;P<0.05),术后7 d,两组患者的水平均有一定的回升,其中试验组患者已接近正常水平,差异均有统计学意义(t=0.020、0.021、0.010,P<0.05)。结论温灸疗法可以促进宫颈癌腹腔镜手术后康复期的患者的早日康复,缩短患者术后的肛门排气时间、住院时间,且对免疫功能的影响较小,能有效提高患者的康复。

Objective Explore the effect of warm moxibustion on the efficacy and immune function of cervical cancer patients after laparoscopic surgery.Methods Seventy-six women who recovered from laparoscopic surgery of cervical cancer in Ningbo Women and Children′s Hospital from August 2016 to July 2018 were selected.The patients were divided into a control group and an experimental group by random number table,each group Of the 38 patients,the experimental group used warm moxibustion therapy and the control group used traditional conventional therapy.The postoperative anal exhaust time,hospitalization time,and T cell subsets and immunoglobulin levels in the immune system were counted in both groups.Results The patients in the experimental group had less postoperative anal exhaustion and hospital stay than the control group,and the differences were statistically significant(t values were 0.020,0.010;P<0.05).After operation,the levels of T cell subsets and immunoglobulin in both groups decreased compared with those before the operation.On the first day after operation,the decrease in CD3^+,CD4^+,and CD8^+in the experimental group was significantly lower than that in the control group(The values were 0.020,0.002,0.005;P<0.05).On the 7 th postoperative day,the levels of the two groups of patients had a certain rebound.Among them,the patients in the experimental group were close to normal levels,and the differences were statistically significant(The values were 0.020,0.033,0.010;P<0.05);on the first day after surgery,the levels of immunoglobulin IgA,IgG,and IgM in the experimental group were significantly lower than those in the control group(t values were0.020,0.002,0.001;P<0.05).On the 7th postoperative day,the levels of the two groups of patients had a certain rebound.Among them,the patients in the experimental group were close to normal levels,and the differences were statistically significant(t values were 0.020,0.021,respectively.0.010;P<0.05).Conclusions Warm moxibustion therapy can promote the early recovery of women after the laparoscopic surgery of cervical cancer,significantly shorten the postoperative anal exhaust time and hospital stay,and have little effect on immune function,which can effectively improve the quality of life of patients,Worthy of clinical promotion.