体医融合模式对女性血压异常人群干预效果研究

Effect of exercise -medical integration intervention on dysarteriotony in women

目的观察体医融合模式对女性正常高值血压和高血压人群干预效果,为体医融合模式的推广提供参考。方法从合肥市庐阳区体医融合慢病干预示范点筛选女性血压异常人群60人,其中正常高值组40人,高血压组20人。体医融合模式干预分线下和线上两部分,线下干预为有组织的集中干预,所有受试者每周2次,每次持续90min,运动强度为40%~60%HRR的有氧运动;线上干预通过奥美微动APP记录受试者运动量,以达到每周120min以上的中等强度有氧运动为有效运动。整个干预期共持续6个月,比较干预前后所有受试者血压、身体成分、血脂及血浆内皮素-1(ET-1)、D-二聚体(D-D)的变化。结果经6个月体医融合干预,正常高值组和高血压组受试者收缩压(SBP)、舒张压(DBP)均显著降低(P<0.01);正常高值组体质量、BMI、体脂肪量、体脂率均显著降低(P<0.01),血浆总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)含量均显著降低(P<0.01),血浆ET-1含量明显降低(P<0.05),D-D含量显著降低(P<0.01);高血压组体质量、BMI显著降低(P<0.01),体脂肪量、体脂率明显降低(P<0.05);血浆TC、LDL-C含量均显著降低(P<0.01),TG含量明显降低(P<0.05),血浆ET-1、D-D含量均显著降低(P<0.01)。结论"政府主导-门部协作-企业运营-专家评估"的体医融合模式可以有效改善女性血压异常人群身体成分,调节血脂及降低血浆ET-1、D-D浓度,降压效果明显,值得推广。

Objective To discuss the effect of exercise-medical integration intervention on normal-high and high blood pressure in women,and to provide reference for the promotion of the exercise-medical integration model.Methods 60 women with abnormal blood pressure(40 with high-normal blood pressure and 20 with hypertension)were selected from Luyang District of Hefei City and were offered both off-line and on-line exercise-medical integration intervention programs.Off-line intervention was conducted by offering a group of subjects 90 minutes aerobic exercise twice a week with 40%to 60%HRR intensity.On-line intervention was conducted by recording the amount of exercise of subjects through Acmeway micro-motion APP,moderate-intensity aerobic exercise over 120 minutes per week was considered as effective exercise.The intervention lasted for 6 months.The changes of blood pressure,body composition,blood lipid and plasma endothelin-1,D-dimer were compared before and after the intervention.Results After 6 months of intervention,SBP and DBP in both high-normal blood pressure group and hypertension group decreased significantly(P<0.01).In high-normal blood pressure group,the body weight,BMI,body fat and body fat rate,plasma levels of TC,TG,LDL-C decreased significantly(P<0.01),plasma level of ET-1 also decreased(P<0.05).In hypertension group,the body weight and BMI,plasma levels of TC,LDL-C,ET-1 and D-D decreased significantly(P<0.01),body fat and body fat rate,plasma TG level also decreased(P<0.05).Conclusions The exercise-medical Integration intervention is a program of"government-led,department-cooperated,enterprise-operated,expertevaluated"which can effectively improve the body composition,regulate blood lipid and reduce plasma levels of ET-1 and D-D in women with dysarteriotony.