2013-2017年金华市中心医院结直肠癌筛查结果分析

Analysis of colorectal cancer screening results in Jinhua Central Hospital from 2013 to 2017

目的分析结直肠癌筛查结果,为结直肠癌的早期发现及预防提供参考。方法回顾性分析2013年1月至2017年12月金华市中心医院筛查结直肠癌患者1569例,包括参加结直肠癌筛查的患者整体情况,不同性别和年龄的患者初筛阳性率,不同初筛结果患者的结肠镜检查依从性,不同性别和年龄的患者结肠镜检查结果。结果筛查结直肠癌1569例,初筛阳性487例,阳性率31.04%。在初筛阳性的患者之中,结肠镜检查106例,检查率21.77%;病变检出16例,检出率15.09%。男性患者的初筛阳性率高于女性患者,差异有统计学意义(χ~2=21.099,P<0.05);≥60周岁患者的初筛阳性率高于<60周岁患者,差异有统计学意义(χ~2=6.544,P<0.05),在全部初筛阳性的487例患者中,危险度评估阳性143例,FOBT阳性291例,上两项均为阳性的53例,三种不同阳性结果人群结肠镜检查阳性率差异有统计学意义(χ~2=43.582,P=0.001)。结论金华市中心医院结直肠癌初筛患者肿瘤结果的阳性率相对较高,参加筛查的男性阳性率要高于女性,大便隐血实验对于肠道疾病诊断的准确性较高。

Objective To analyze the initial screening data of colorectal cancer and to provide a reference for early detection and prevention of colorectal cancer.Methods Based on the inclusion and exclusion criteria,a retrospective analysis was performed on the data of 1569 patients who were screened for colorectal cancer in Jinhua Municipal Central Hospital from January 2013 to December 2017,including the demographic information,the positive rate,the colonoscopy compliance and the colonoscopy results.Results 487 were found to be positive with the positive rate of 31.04%.Colonoscopy was performed in 106 of 487(21.77%)of positive cases and 16(15.09%)were found of having local lesions.The positive rates of initial screening were significantly higher in men than that in women(χ~2=21.099,P<0.05)and in subjects aged 60 years and above(χ~2=6.544,P<0.05).Among 487 with positive initial screening results,143 were positive for risk assessment,291 were positive for FOBT and 53 were positive for both,the differences were statistically significant(χ~2=43.582,P=0.001).Conclusions The positive rate of colorectal cancer screening in Jinhua Municipal Central Hospital is relatively high especially in men.Stool occult blood test is accurate for the diagnosis of intestinal diseases.