鱼类实验动物封闭群和近交系资源培育现状

Current situation of the breeding of closed colony and inbred strains of fish as laboratory animals

鱼类实验动物的应用研究已经深入生命科学的各个领域,取得了许多重大研究成果,因国内外实验鱼在来源、代系、培育和管理方式等背景上均较为复杂,为实验鱼质量控制带来诸多不便。针对鱼类实验动物资源培育现状,本文综述了国内外实验鱼封闭群和近交系的培育、管理和标准化等方面的现状和存在的问题,以期为我国实验鱼培育管理和质量控制标准化提供参考。

As an important component of laboratory animals,the applied research of laboratory fish has expanded to all fields of bioscience,making significant contributions to scientific research.The standardization study of quality control of laboratory fish has encountered issues due to complications regarding the source,generation,breeding,and management of laboratory fish.This paper reviews the current situation regarding the breeding,management,and standardization study of closed colony and inbred strains of laboratory fish at home and abroad.The paper also analyzes current problems,aiming at providing references for the breeding,management,and standardization study of quality control of laboratory fish in China.