中国如何最大程度地降低脊髓灰质炎病毒泄露风险

How can China minimize facility-associated risk of poliovirus release

在消灭特定型别野生脊髓灰质炎(脊灰)病毒后,源自保存脊灰病毒设施泄漏的病毒,会增加已经消灭病毒在人群中重新传播的风险。中国目前尚未制定封存脊灰病毒的完整方案,封存工作的进展滞后于全球的要求。为了在中国最大程度地降低脊灰病毒泄露的风险,相关权威机构需要依据国家法规和部门规章,登记清册脊灰病毒并评价工作质量,建立机制,定期更新持有Sabin株脊灰病毒或潜在感染性材料清单;销毁非必需设施保存的Ⅱ型Sabin株脊灰病毒和潜在感染性材料;重点关注必需设施持有的脊灰病毒,建立国家脊灰病毒封存监管机构认证的必需设施。

After eradication of type-specific wild poliovirus,polioviruses released from poliovirus-retaining facilities increase the risk of retransmission of eradicated polioviruses in the population.China has not yet developed a complete action plan for poliovirus containment,and progress toward containment lags behind global requirements.To minimize facility-associated risk of poliovirus release in China,relevant authorities should(1)complete a poliovirus inventory and evaluate its quality in accordance with national regulations and departmental requirements,(2)establish a mechanism for regularly updating the inventory of Sabin polioviruses or potential infectious materials,(3)destroy typeⅡpolioviruses and potential infectious materials retained in unessential facilities,and(4)establish essential facilities certified by national authorities for poliovirus containment to focus on oversight of their polioviruses.