癌基因与抑癌基因在伯基特淋巴瘤发生发展中的研究进展

Advances in study on role of oncogene and anti-oncogene in pathogenesis and development of Burkitt’s lymphoma

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摘要伯基特淋巴瘤(Burkitt's lymphoma,以下称Burkitt淋巴瘤)是一种B细胞非霍奇金淋巴瘤,呈高度侵袭性,好发于儿童和青年,约占儿童及青少年非霍奇淋巴瘤的30%,男性发病明显多于女性。此外,患者常以癌基因MYC易位和EB病毒(Epstein-Barr virus,EBV)感染为特征。依据流行病学特征,世界卫生组织将Burkitt淋巴瘤进一步分为地方型、散发型与免疫缺陷型。地方型Burkitt淋巴瘤主要发生于非洲,几乎所有患者均存在EBV感染。

作者房莹吴东常春康

机构地区上海交通大学附属第六人民医院血液科

出处《诊断学理论与实践》 2019年第6期630-633,共4页 Journal of Diagnostics Concepts & Practice

基金上海市卫生健康委员会科研课题基金(20124275).

关键词癌基因抑癌基因机制伯基特淋巴瘤

分类号 R733.1 [医药卫生—肿瘤]

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共引文献2

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诊断学理论与实践

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癌基因与抑癌基因在伯基特淋巴瘤发生发展中的研究进展

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