摘要
Varicella-zoster virus(VZV)belongs to a neurotropic Alphaherpesvirinae and is the causative pathogen of both the varicella and herpes zoster.Currently,there are three different vaccines for the prevention,low does live-attenuated Oka(v Oka)against varicella,high does v Oka and glycoprotein E with the AS01B adjuvant system against zoster.Varicella vaccine containing v Oka effectively prevents varicella,but latency of v Oka can be detected in the inoculated population and its reactivation causes zoster.
