2019—2021年广东省云浮市妇幼保健院0~10岁儿童维生素D水平

Vitamin D levels among children aged 0-10 in Women’s and Children’s Health Hospital of Yunfu from 2019 to 2021,Guangdong Province

目的了解2019—2021年广东省云浮市0~10岁儿童25-羟基维生素D[25(OH)D]的水平,为指导本地区0~10岁儿童维生素D补充提供科学依据。方法收集2019年1月—2021年10月在广东省云浮市妇幼保健院儿童保健科进行健康体检的6208例儿童血清25(OH)D水平情况,分析比较不同性别、年龄、季节对血清25(OH)D水平的影响。结果6208例0~10岁儿童的25(OH)D平均水平为(41.40±13.44)ng/mL,25(OH)D水平在不同性别间的比较差异无统计学意义(P>0.05)。男童血清25(OH)D缺乏和不足比例低于女童,充足比例高于女童(χ^(2)=19.057,P<0.001)。随着儿童年龄的增长,血清25(OH)D水平下降,0~<1岁儿童血清25(OH)D平均水平最高[(49.05±14.17)ng/mL],7~10岁最低[(31.09±7.65)ng/mL],不同年龄段儿童的血清25(OH)D水平比较,差异有统计学意义(F=350.097,P<0.001)。春季儿童血清25(OH)D水平最高,秋季最低,4个季节差异有统计学意义(F=45.809,P<0.001)。结论应关注和重视学龄前儿童维生素D的营养状况,适当增加儿童户外活动的时间,积极开展家庭宣教。

Objective To investigate the 25(OH)D level in children aged 0-10 years old in Yunfu,Guangdong,so as to providescientific evidence for vitamin D supplement guidance in this area.Methods The serum 25(OH)D levels of 6208 children who underwentphysical examination in the Women’s and Children’s Health Hospital of Yunfu from January 2019 to October 2021 were analyzedretrospectively.The effects of gender,age and season on the serum 25(OH)D levels were statistically analyzed.Results The average level ofserum 25(OH)D in 6208 children aged 0-10 years old was(41.40±13.44)ng/mL.There was no significant difference in the level of serum25(OH)D between different genders(P>0.05).The proportion of boys with 25(OH)D deficiency was lower than that of girls,and theproportion of boys with 25(OH)D sufficiency was higher than that of girls(χ^(2)=19.057,P<0.001).With the increasing of children’s age,theserum 25(OH)D level decreased.The average level of infants 0-<1[(49.05±14.17)ng/mL]was the highest and that of 7-10 age groupwas the lowest[(31.09±7.65)ng/mL].There was significant difference in the serum 25(OH)D level between different age groups(F=350.097,P<0.001).The serum 25(OH)D level in spring was the highest and that in autumn was the lowest.The serum 25(OH)D level inthe four seasons were statistically different(F=45.809,P<0.001).Conclusion Nutritional status of vitamin D in preschool children shouldbe paid attention to,children’s outdoor activities should be increased appropriately,and family education should be carried out actively.